PYGM Peptide - Middle Region Blocking Peptide

Name: PYGM Peptide - Middle Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3247111
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3247111

This is a synthetic peptide designed for use in combination with anti- PYGM Antibody, madeTarget Description: This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain.… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PYGM, Blocking Peptide

Full Product Name

PYGM Peptide - middle region

Product Gene Name

PYGM blocking peptide

Sequence

Synthetic peptide located within the following region: QMEEADDWLR YGNPWEKARP EFTLPVHFYG HVEHTSQGAK WVDTQVVLAM

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

PYGM peptide (MBS3247111) is used for blocking the activity of PYGM antibody (MBS3222440)

Molecular Weight

82 kDa

OMIM

232600

Product Categories/Family for PYGM blocking peptide

Peptide

Other Notes

Small volumes of PYGM blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PYGM purchase

MBS3247111 is a blocking peptide targeting PYGM. Also known as PYGM Peptide - middle region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for PYGM. It may not necessarily be applicable to this product.

NCBI GI #

5032009

NCBI GeneID

5837

NCBI Accession #

NP_001158188.1

UniProt Primary Accession #

P11217

UniProt Related Accession #

P11217

GenBank Nucleotide #

NM_001164716.1

NCBI Official Full Name

glycogen phosphorylase, muscle form isoform 1

NCBI Official Synonym Full Names

glycogen phosphorylase, muscle associated

NCBI Official Symbol

PYGM

UniProt Protein Name

Glycogen phosphorylase, muscle form

UniProt Synonym Protein Names

Myophosphorylase

Protein Family

Glycogen phosphorylase

UniProt Gene Name

PYGM

UniProt Entry Name

PYGM_HUMAN

NCBI Protein Information

glycogen phosphorylase, muscle form

NCBI Summary for PYGM

This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]

UniProt Comments for PYGM

PYGM: an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Dimers associate into a tetramer to form the enzymatically active phosphorylase A. Phosphorylation of Ser-14 converts phosphorylase B (unphosphorylated) to phosphorylase A.

Protein type: Phosphorylase; Carbohydrate Metabolism - starch and sucrose; Transferase; Endoplasmic reticulum; EC 2.4.1.1

Chromosomal Location of Human Ortholog: 11q12-q13.2

Cellular Component: cytosol

Molecular Function: glycogen phosphorylase activity; nucleotide binding; pyridoxal phosphate binding

Biological Process: glycogen metabolic process; glycogen catabolic process; carbohydrate metabolic process; glucose metabolic process; pathogenesis

Disease: Glycogen Storage Disease V

Research Articles on PYGM

1. Results show that PYGM and RAC1 are altered in the dorsolateral prefrontal cortex in chronic schizophrenia and are controlled by NMDA signaling in the rodent cortex and cortical astrocytes suggesting an altered NMDA-dependent glycogenolysis in astrocytes in schizophrenia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PYGM blocking peptide

Reference Product	PubMed Publications
FAU blocking peptide	>4 publications with PYGM and FAU
PHKB blocking peptide	>3 publications with PYGM and PHKB
GBE1 blocking peptide	>2 publications with PYGM and GBE1
PHKA1 blocking peptide	>2 publications with PYGM and PHKA1
PFKM blocking peptide	>1 publications with PYGM and PFKM
PHKG1 blocking peptide	>1 publications with PYGM and PHKG1

Pathways associated with PYGM blocking peptide

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glucose Metabolism Pathway antibodies	Glucose Metabolism Pathway Diagram
Glycogen Metabolism Pathway antibodies	Glycogen Metabolism Pathway Diagram
Glycogen Breakdown (glycogenolysis) Pathway antibodies	Glycogen Breakdown (glycogenolysis) Pathway Diagram
Glycogen Storage Diseases Pathway antibodies	Glycogen Storage Diseases Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Carbohydrates Pathway antibodies	Metabolism Of Carbohydrates Pathway Diagram
Myoclonic Epilepsy Of Lafora Pathway antibodies	Myoclonic Epilepsy Of Lafora Pathway Diagram

Diseases associated with PYGM blocking peptide

Disease Name	Pubmed Publications
Neoplasms Antibodies	>65 publications with PYGM and Neoplasms
Glycogen Storage Disease Type V Antibodies	>59 publications with PYGM and Glycogen Storage Disease Type V
Nervous System Diseases Antibodies	>22 publications with PYGM and Nervous System Diseases
Adenocarcinoma Antibodies	>15 publications with PYGM and Adenocarcinoma
Hyperplasia Antibodies	>10 publications with PYGM and Hyperplasia
Muscular Diseases Antibodies	>9 publications with PYGM and Muscular Diseases
Lung Neoplasms Antibodies	>7 publications with PYGM and Lung Neoplasms
Breast Neoplasms Antibodies	>6 publications with PYGM and Breast Neoplasms
Liver Diseases Antibodies	>2 publications with PYGM and Liver Diseases
Skin Neoplasms Antibodies	>2 publications with PYGM and Skin Neoplasms

Organs/Tissues associated with PYGM blocking peptide

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>85 publications with PYGM and Muscle
Blood Antibodies	>16 publications with PYGM and Blood
Pancreas Antibodies	>9 publications with PYGM and Pancreas
Liver Antibodies	>8 publications with PYGM and Liver
Lung Antibodies	>8 publications with PYGM and Lung
Eye Antibodies	>4 publications with PYGM and Eye
Brain Antibodies	>4 publications with PYGM and Brain
Heart Antibodies	>4 publications with PYGM and Heart
Nerve Antibodies	>3 publications with PYGM and Nerve
Uterus Antibodies	>1 publications with PYGM and Uterus