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RLN2 Peptide - Middle Region Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3245202

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The active form of the… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RLN2, Blocking Peptide
Full Product Name
RLN2 Peptide - middle region
Product Gene Name
Product Synonym Gene Name
H2; RLXH2; H2-RLX; bA12D24.1.1; bA12D24.1.2
Sequence
Synthetic peptide located within the following region: FKKLIRNRQS EAADSSPSEL KYLGLDTHSR KKRQLYSALA NKCCHVGCTK
Species Reactivity
Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
RLN2 peptide (MBS3245202) is used for blocking the activity of RLN2 antibody (MBS3220401)
Molecular Weight
21 kDa
OMIM
179740

Product Categories/Family for RLN2 blocking peptide

Applications Tested/Suitable for RLN2 blocking peptide
Western Blot (WB)

Other Notes

Small volumes of RLN2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RLN2 purchase

MBS3245202 is a blocking peptide targeting RLN2. Also known as RLN2 Peptide - middle region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for RLN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
prorelaxin H2 isoform 2
NCBI Official Synonym Full Names
relaxin 2
NCBI Official Symbol
RLN2
NCBI Official Synonym Symbols
H2; RLXH2; H2-RLX; bA12D24.1.1; bA12D24.1.2
UniProt Protein Name
Prorelaxin H2
Protein Family
UniProt Gene Name
RLN2
UniProt Entry Name
REL2_HUMAN
NCBI Protein Information
prorelaxin H2

NCBI Summary for RLN2

This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016]
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UniProt Comments for RLN2

RLN2: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. Belongs to the insulin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: female pregnancy
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with RLN2 blocking peptide

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