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SIM2 Peptide - Middle Region Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3226453

This is a synthetic peptide designed for use in combination with anti-SIM2 Antibody, madeTarget Description: This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of… More details

$195 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SIM2, Blocking Peptide
Full Product Name
SIM2 Peptide - middle region
Product Gene Name
Product Synonym Gene Name
SIM2;BHLHE15;
Sequence
Synthetic peptide located within the following region: VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
Species Reactivity
Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
SIM2 peptide (MBS3226453) is used for blocking the activity of SIM2 antibody (MBS3201432)
Molecular Weight
73kDa
OMIM
600892

Product Categories/Family for SIM2 blocking peptide

Other Notes

Small volumes of SIM2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIM2 purchase

MBS3226453 is a blocking peptide targeting SIM2. Also known as SIM2 Peptide - middle region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for SIM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Single-minded homolog 2
NCBI Official Synonym Full Names
SIM bHLH transcription factor 2
NCBI Official Symbol
SIM2
NCBI Official Synonym Symbols
SIM; bHLHe15; HMC13F06; HMC29C01
UniProt Protein Name
Single-minded homolog 2
UniProt Synonym Protein Names
Class E basic helix-loop-helix protein 15; bHLHe15
Protein Family
UniProt Gene Name
SIM2
UniProt Synonym Gene Names
BHLHE15; bHLHe15
UniProt Entry Name
SIM2_HUMAN
NCBI Protein Information
single-minded homolog 2

NCBI Summary for SIM2

This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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UniProt Comments for SIM2

SIM2: Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; DNA-binding

Chromosomal Location of Human Ortholog: 21q22.13

Cellular Component: nucleoplasm

Molecular Function: signal transducer activity; DNA binding; protein heterodimerization activity; transcription factor activity

Biological Process: nervous system development; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; embryonic pattern specification; cell differentiation; signal transduction; lung development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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