SSH3 Peptide - N-Terminal Region Blocking Peptide

Name: SSH3 Peptide - N-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3247508
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3247508

This is a synthetic peptide designed for use in combination with anti- SSH3 Antibody, madeTarget Description: The ADF (actin-depolymerizing factor)/cofilin family is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SSH3, Blocking Peptide

Full Product Name

SSH3 Peptide - N-terminal region

Product Gene Name

SSH3 blocking peptide

Product Synonym Gene Name

SSH3L

Sequence

Synthetic peptide located within the following region: EEELHGDQTD FGQGSQSPQK QEEQRQHLHL MVQLLRPQDD IRLAAQLEAP

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

SSH3 peptide (MBS3247508) is used for blocking the activity of SSH3 antibody (MBS3222841)

Molecular Weight

51 kDa

OMIM

606780

Product Categories/Family for SSH3 blocking peptide

Peptide

Other Notes

Small volumes of SSH3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSH3 purchase

MBS3247508 is a blocking peptide targeting SSH3. Also known as SSH3 Peptide - N-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for SSH3. It may not necessarily be applicable to this product.

NCBI GI #

239582767

NCBI GeneID

54961

NCBI Accession #

NP_060327.3

UniProt Primary Accession #

Q8TE77

UniProt Related Accession #

Q8TE77

GenBank Nucleotide #

NM_017857.3

NCBI Official Full Name

protein phosphatase Slingshot homolog 3

NCBI Official Synonym Full Names

slingshot protein phosphatase 3

NCBI Official Symbol

SSH3

NCBI Official Synonym Symbols

SSH3L

UniProt Protein Name

Protein phosphatase Slingshot homolog 3

UniProt Synonym Protein Names

SSH-like protein 3

Protein Family

Protein phosphatase Slingshot

UniProt Gene Name

SSH3

UniProt Synonym Gene Names

SSH3L; SSH-3L; hSSH-3L

UniProt Entry Name

SSH3_HUMAN

NCBI Protein Information

protein phosphatase Slingshot homolog 3

NCBI Summary for SSH3

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008]

UniProt Comments for SSH3

SSH3: a protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Does not bind to, or colocalize with, filamentous actin. Five alternatively spliced isoforms have been described.

Protein type: Protein phosphatase, dual-specificity; Protein phosphatase, Ser/Thr (non-receptor); Phosphatase; Motility/polarity/chemotaxis; EC 3.1.3.48; Cytoskeletal; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: cytoskeleton; cytoplasm; nucleus

Molecular Function: DNA binding; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; actin binding

Biological Process: regulation of actin polymerization and/or depolymerization; regulation of axonogenesis; protein amino acid dephosphorylation

Research Articles on SSH3

1. Expression of phosphatase-dead versions of SSH proteins, SSH1, SSH2 & SSH3 results in phosphorylation/inactivation of cofilin, changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SSH3 blocking peptide

Reference Product	PubMed Publications
LIMK1 blocking peptide	>1 publications with SSH3 and LIMK1

Pathways associated with SSH3 blocking peptide

Products by Pathway	Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram

Organs/Tissues associated with SSH3 blocking peptide

Organ/Tissue Name	Pubmed Publications
Thyroid Antibodies	>1 publications with SSH3 and Thyroid
Muscle Antibodies	>1 publications with SSH3 and Muscle
Lung Antibodies	>1 publications with SSH3 and Lung
Brain Antibodies	>1 publications with SSH3 and Brain