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VIM (Vimentin) (VIM) CLIA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2531792

Intended Uses: This CLIA kit applies to the in vitro quantitative determination of VIM concentrations in serum, plasma and other biological fluids.Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has… More details

$670 / 96 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VIM (Vimentin), CLIA Kit
Full Product Name
Human VIM (Vimentin) CLIA Kit
Product Gene Name
VIM clia kit
Species Reactivity
Human
Assay Type
Sandwich
Detection Range
62.5-4000pg/mL
Sensitivity
Min: 37.5pg/mL; Max: 4000pg/mL
Specificity
This kit recognizes natural and recombinant VIM. No significant cross-reactivity or interference between VIM and analogues was observed.
Molecular Weight
53,652 Da
OMIM
116300
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of VIM clia kit

Human VIM CLIA Kit – Cat# MBS2531792

Other Notes

Small volumes of VIM clia kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VIM purchase

MBS2531792 is a CLIA kit targeting VIM. Also known as Human VIM (Vimentin) CLIA Kit. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for VIM. It may not necessarily be applicable to this product.

NCBI GI #
62414289
NCBI GeneID
7431
NCBI Accession #
NP_003371.2
UniProt Secondary Accession #
Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3; B0YJC2; D3DRU4
UniProt Related Accession #
P08670
GenBank Nucleotide #
NM_003380.3
NCBI Official Full Name
vimentin
NCBI Official Synonym Full Names
vimentin
NCBI Official Symbol
VIM
NCBI Official Synonym Symbols
HEL113; CTRCT30
UniProt Protein Name
Vimentin
Protein Family
Vimentin
UniProt Gene Name
VIM
UniProt Entry Name
VIME_HUMAN
NCBI Protein Information
vimentin

NCBI Summary for VIM

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]
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UniProt Comments for VIM

Vimentin: an intermediate filament protein. Intermediate filament proteins are expressed in a tissue-specific manner. Desmin is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: cytoplasm; cytoskeleton; cytosol; focal adhesion; intermediate filament; intermediate filament cytoskeleton; leading edge; neuron projection; peroxisome; plasma membrane

Molecular Function: double-stranded RNA binding; glycoprotein binding; identical protein binding; protein binding; protein C-terminus binding; structural constituent of cytoskeleton; structural constituent of eye lens

Biological Process: apoptosis; astrocyte development; Bergmann glial cell differentiation; cell motility; cell structure disassembly during apoptosis; intermediate filament organization; muscle filament sliding; programmed cell death; viral reproduction

Disease: Cataract 30
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Research Articles on VIM

1. vimentin, survivin and p53 may have a role in clear cell renal cell carcinoma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with VIM clia kit

 Reference Product  PubMed Publications
 CASP3 clia kit  >6 publications with VIM and CASP3
 AKT1 clia kit  >4 publications with VIM and AKT1
 TPM3 clia kit  >1 publications with VIM and TPM3
 CASP8 clia kit  >1 publications with VIM and CASP8

Pathways associated with VIM clia kit

 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Caspase Cascade In Apoptosis Pathway antibodies  Caspase Cascade In Apoptosis Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram

Organs/Tissues associated with VIM clia kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >524 publications with VIM and Brain
 Blood Antibodies  >231 publications with VIM and Blood
 Muscle Antibodies  >125 publications with VIM and Muscle
 Nerve Antibodies  >86 publications with VIM and Nerve
 Bone Antibodies  >84 publications with VIM and Bone
 Kidney Antibodies  >66 publications with VIM and Kidney
 Liver Antibodies  >62 publications with VIM and Liver
 Bone Marrow Antibodies  >53 publications with VIM and Bone Marrow
 Eye Antibodies  >49 publications with VIM and Eye
 Lung Antibodies  >46 publications with VIM and Lung
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