Human APO A1-Ab ELISA Kit – Cat# MBS2500174

Apo A1-Ab ELISA Kit for Human

Name: Human APO A1-Ab ELISA Kit; Apo A1-Ab; MyBioSource
Brand: MyBioSource
SKU: MBS2500174
Price: 300 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2500174

Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of Apo A1-Ab in human serum, plasma and other biological fluidsPrinciple of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided… More details

$300 / 24 Tests (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Apo A1-Ab, ELISA Kit

Full Product Name

Human Apo A1-Ab (Anti-Apolipoprotein A1 Antibody) ELISA Kit

Product Gene Name

Apo A1-Ab elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Biological Fluids

Detection Range

3.125-200ng/mL

Sensitivity

Min: 1.875ng/mL; Max: 200ng/mL

Specificity

This assay has high sensitivity and excellent specificity for detection of Human Apo A1-Ab. No significant cross-reactivity or interference between Human Apo A1-Ab and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human Apo A1-Ab and all the analogues, therefore, cross reaction may still exist.

Preparation and Storage

Store at 4 degree C.

Molecular Weight

11,175 Da

OMIM

107670

3D Structure

ModBase 3D Structure for P02652

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Apo A1-Ab elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Apo A1-Ab purchase

MBS2500174 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apo A1-Ab, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Apo A1-Ab. The ELISA analytical biochemical technique of the MBS2500174 kit is based on Apo A1-Ab antibody-Apo A1-Ab antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Apo A1-Ab antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Apo A1-Ab. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Apo A1-Ab. It may not necessarily be applicable to this product.

NCBI GI #

4502149

NCBI GeneID

336

NCBI Accession #

NP_001634.1

UniProt Primary Accession #

P02652

UniProt Secondary Accession #

B2R524

UniProt Related Accession #

P02652

GenBank Nucleotide #

NM_001643.1

NCBI Official Full Name

apolipoprotein A-II preproprotein

NCBI Official Synonym Full Names

apolipoprotein A-II

NCBI Official Symbol

APOA2

NCBI Official Synonym Symbols

apoAII; Apo-AII; ApoA-II

UniProt Protein Name

Apolipoprotein A-II

UniProt Synonym Protein Names

Apolipoprotein A2Cleaved into the following 2 chains:Proapolipoprotein A-II; ProapoA-II; Truncated apolipoprotein A-IIAlternative name(s):Apolipoprotein A-II(1-76)

UniProt Gene Name

APOA2

UniProt Synonym Gene Names

Apo-AII; ApoA-II; ProapoA-II

UniProt Entry Name

APOA2_HUMAN

NCBI Protein Information

apolipoprotein A-II; apolipoprotein A2

NCBI Summary for Apo A1-Ab

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]

UniProt Comments for Apo A1-Ab

APOA2: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Belongs to the apolipoprotein A2 family.

Protein type: Secreted, signal peptide; Endoplasmic reticulum; Lipid-binding; Secreted

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: chylomicron; endoplasmic reticulum lumen; early endosome; extracellular region; cytosol

Molecular Function: lipid transporter activity; protein binding; protein homodimerization activity; lipase inhibitor activity; protein heterodimerization activity; cholesterol transporter activity; cholesterol binding; phospholipid binding; phosphatidylcholine binding; high-density lipoprotein binding; lipid binding; apolipoprotein receptor binding

Biological Process: positive regulation of catalytic activity; phototransduction, visible light; protein folding; viral reproduction; negative regulation of cholesterol transport; response to glucocorticoid stimulus; regulation of protein stability; diacylglycerol catabolic process; positive regulation of lipid catabolic process; cellular lipid metabolic process; negative regulation of lipase activity; negative regulation of lipid catabolic process; phospholipid efflux; regulation of cholesterol absorption; response to glucose stimulus; retinoid metabolic process; response to drug; cholesterol metabolic process; organ regeneration; protein amino acid oxidation; phospholipid catabolic process; positive regulation of interleukin-8 biosynthetic process; lipoprotein metabolic process; cholesterol efflux; negative regulation of cytokine secretion during immune response; cholesterol homeostasis; triacylglycerol metabolic process; reverse cholesterol transport; response to estrogen stimulus; peptidyl-methionine modification; phosphatidylcholine biosynthetic process; acute inflammatory response

Disease: Hypercholesterolemia, Familial

Research Articles on Apo A1-Ab

1. Apolipoprotein A-II and the regulation of high density lipoproteins in cardiovascular disease. [Review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Apo A1-Ab elisa kit

Reference Product	PubMed Publications
APOA1 elisa kit	>40 publications with Apo A1-Ab and APOA1
APOE elisa kit	>17 publications with Apo A1-Ab and APOE
APOB elisa kit	>17 publications with Apo A1-Ab and APOB
APOC2 elisa kit	>12 publications with Apo A1-Ab and APOC2
APOC3 elisa kit	>11 publications with Apo A1-Ab and APOC3
APOA4 elisa kit	>5 publications with Apo A1-Ab and APOA4
LPL elisa kit	>4 publications with Apo A1-Ab and LPL
APOA5 elisa kit	>4 publications with Apo A1-Ab and APOA5
APOH elisa kit	>3 publications with Apo A1-Ab and APOH

Pathways associated with Apo A1-Ab elisa kit

Products by Pathway	Pathway Diagram
Chylomicron-mediated Lipid Transport Pathway antibodies	Chylomicron-mediated Lipid Transport Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Associated With Visual Transduction Pathway antibodies	Diseases Associated With Visual Transduction Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Lipid Digestion, Mobilization, And Transport Pathway antibodies	Lipid Digestion, Mobilization, And Transport Pathway Diagram
Lipoprotein Metabolism Pathway antibodies	Lipoprotein Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram

Diseases associated with Apo A1-Ab elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>21 publications with Apo A1-Ab and Cardiovascular Diseases
Dyslipidemias Antibodies	>16 publications with Apo A1-Ab and Dyslipidemias
Liver Diseases Antibodies	>13 publications with Apo A1-Ab and Liver Diseases
Hyperlipidemias Antibodies	>12 publications with Apo A1-Ab and Hyperlipidemias
Heart Diseases Antibodies	>12 publications with Apo A1-Ab and Heart Diseases
Inflammation Antibodies	>8 publications with Apo A1-Ab and Inflammation
Kidney Diseases Antibodies	>6 publications with Apo A1-Ab and Kidney Diseases
Carcinoma, Hepatocellular Antibodies	>5 publications with Apo A1-Ab and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>5 publications with Apo A1-Ab and Liver Neoplasms
Hypertriglyceridemia Antibodies	>5 publications with Apo A1-Ab and Hypertriglyceridemia

Organs/Tissues associated with Apo A1-Ab elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>69 publications with Apo A1-Ab and Blood
Liver Antibodies	>25 publications with Apo A1-Ab and Liver
Heart Antibodies	>14 publications with Apo A1-Ab and Heart
Kidney Antibodies	>9 publications with Apo A1-Ab and Kidney
Muscle Antibodies	>5 publications with Apo A1-Ab and Muscle
Intestine Antibodies	>5 publications with Apo A1-Ab and Intestine
Brain Antibodies	>3 publications with Apo A1-Ab and Brain
Placenta Antibodies	>3 publications with Apo A1-Ab and Placenta
Lung Antibodies	>2 publications with Apo A1-Ab and Lung
Spleen Antibodies	>2 publications with Apo A1-Ab and Spleen