Arginase, Arg (ARG) ELISA Kit for Human

Name: Human ARG ELISA Kit; Arginase, Arg; MyBioSource
Brand: MyBioSource
SKU: MBS9302171
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9302171

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of Arg (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates,… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Arginase, Arg, ELISA Kit

Full Product Name

Human Arginase, Arg ELISA Kit

Product Gene Name

Arg elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Human Body Fluids, Tissue Homogenates, Secretions Or Feces Samples

Detection Range

0.625ng/ml-20ng/ml

Sensitivity

0.1ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

34,735 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (131894344..131905472). Location: 6q23

OMIM

207800

3D Structure

ModBase 3D Structure for P05089

Other Notes

Small volumes of Arg elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Arg purchase

MBS9302171 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Arginase, Arg, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Arg. The ELISA analytical biochemical technique of the MBS9302171 kit is based on Arg antibody-Arg antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Arg antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Arg. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Arg. It may not necessarily be applicable to this product.

NCBI GI #

1197498

NCBI GeneID

383

NCBI Accession #

CAA31188.1

UniProt Primary Accession #

P05089

UniProt Secondary Accession #

Q5JWT5; Q5JWT6; Q8TE72; Q9BS50; A6NEA0

UniProt Related Accession #

P05089

NCBI Official Full Name

arginase

NCBI Official Synonym Full Names

arginase, liver

NCBI Official Symbol

ARG1

UniProt Protein Name

Arginase-1

UniProt Synonym Protein Names

Liver-type arginase; Type I arginase

UniProt Gene Name

ARG1

UniProt Entry Name

ARGI1_HUMAN

NCBI Protein Information

arginase-1; type I arginase; liver-type arginase

NCBI Summary for Arg

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

UniProt Comments for Arg

ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.3.1; Hydrolase; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 6q23

Cellular Component: extracellular space; neuron projection; cell soma; cytoplasm; nucleus; cytosol

Molecular Function: manganese ion binding; arginase activity

Biological Process: response to drug; mammary gland involution; maternal process involved in pregnancy; response to herbicide; liver development; response to amino acid stimulus; response to vitamin A; response to manganese ion; response to vitamin E; response to selenium ion; response to cadmium ion; response to zinc ion; response to methylmercury; arginine catabolic process; positive regulation of endothelial cell proliferation; response to axon injury; collagen biosynthetic process; urea cycle; lung development; response to amine stimulus

Disease: Argininemia

Research Articles on Arg

1. The tumor suppressive function of arginase-I in both infiltrating and circulating myeloid-derived suppressor cells is a downstream target of activated STAT3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Arg elisa kit

Reference Product	PubMed Publications
NOS2 elisa kit	>35 publications with Arg and NOS2
IL13 elisa kit	>10 publications with Arg and IL13
NOS3 elisa kit	>7 publications with Arg and NOS3
NOS1 elisa kit	>5 publications with Arg and NOS1
ASL elisa kit	>5 publications with Arg and ASL
OTC elisa kit	>4 publications with Arg and OTC
OAT elisa kit	>2 publications with Arg and OAT

Pathways associated with Arg elisa kit

Products by Pathway	Pathway Diagram
ATF-2 Transcription Factor Network Pathway antibodies	ATF-2 Transcription Factor Network Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
IL4-mediated Signaling Events Pathway antibodies	IL4-mediated Signaling Events Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram

Diseases associated with Arg elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>68 publications with Arg and Inflammation
Neoplasms Antibodies	>59 publications with Arg and Neoplasms
Disease Models, Animal Antibodies	>38 publications with Arg and Disease Models, Animal
Nervous System Diseases Antibodies	>35 publications with Arg and Nervous System Diseases
Immune System Diseases Antibodies	>32 publications with Arg and Immune System Diseases
Necrosis Antibodies	>24 publications with Arg and Necrosis
Asthma Antibodies	>21 publications with Arg and Asthma
Pain Antibodies	>20 publications with Arg and Pain
Cardiovascular Diseases Antibodies	>20 publications with Arg and Cardiovascular Diseases
Lung Neoplasms Antibodies	>20 publications with Arg and Lung Neoplasms

Organs/Tissues associated with Arg elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>153 publications with Arg and Blood
Muscle Antibodies	>100 publications with Arg and Muscle
Brain Antibodies	>70 publications with Arg and Brain
Lung Antibodies	>67 publications with Arg and Lung
Liver Antibodies	>43 publications with Arg and Liver
Eye Antibodies	>25 publications with Arg and Eye
Bone Marrow Antibodies	>20 publications with Arg and Bone Marrow
Spleen Antibodies	>15 publications with Arg and Spleen
Skin Antibodies	>12 publications with Arg and Skin
Uterus Antibodies	>9 publications with Arg and Uterus