Casein Beta (CSN2) ELISA Kit for Human

Name: Human CSN2 ELISA Kit; Casein Beta; MyBioSource
Brand: MyBioSource
SKU: MBS2019166
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2019166

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Casein Beta (CSN2). Standards or samples are then added to the appropriate microtiter plate wells… More details

$425 / 24-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Casein Beta (CSN2), ELISA Kit

Full Product Name

Human Casein Beta (CSN2) ELISA Kit

Product Gene Name

CSN2 elisa kit

Product Synonym Names

CASb

Species Reactivity

Human

Assay Type

Double-antibody Sandwich

Samples

Breast milk and other biological fluids

Detection Range

7.8-500ng/mL

Sensitivity

3.3ng/mL

Specificity

This assay has high sensitivity and excellent specificity for detection of Casein Beta (CSN2).
No significant cross-reactivity or interference between Casein Beta (CSN2) and analogues was observed.

Preparation and Storage

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Molecular Weight

25,382 Da

OMIM

115460

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Application

Enzyme-linked immunosorbent assay for Antigen Detection.

Intra-assay Precision (Precision within an assay)

3 samples with low, middle and high level Casein Beta (CSN2) were tested 20 times on one plate, respectively.

Inter-assay Precision (Precision between assays)

3 samples with low, middle and high level Casein Beta (CSN2) were tested on 3 different plates, 8 replicates in each plate.

CV(%) =

SD/meanX100

Intra-Assay

CV<10%

Inter-Assay

CV<12%

Product Categories/Family for CSN2 elisa kit

Signal Transduction

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of CSN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSN2 purchase

MBS2019166 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Casein Beta (CSN2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CSN2. The ELISA analytical biochemical technique of the MBS2019166 kit is based on CSN2 antibody-CSN2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CSN2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CSN2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CSN2. It may not necessarily be applicable to this product.

NCBI GI #

64654755

NCBI GeneID

1447

NCBI Accession #

AAH96197.1

UniProt Secondary Accession #

Q4VAZ9; Q9UCM5

UniProt Related Accession #

P05814

NCBI Official Full Name

Casein beta

NCBI Official Synonym Full Names

casein beta

NCBI Official Symbol

CSN2

NCBI Official Synonym Symbols

CASB

UniProt Protein Name

Beta-casein

Protein Family

Beta-casein

UniProt Gene Name

CSN2

UniProt Synonym Gene Names

CASB

UniProt Entry Name

CASB_HUMAN

NCBI Protein Information

beta-casein

NCBI Summary for CSN2

This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

UniProt Comments for CSN2

CSN2: Important role in determination of the surface properties of the casein micelles. Belongs to the beta-casein family.

Protein type: Calcium-binding; Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: extracellular space; extracellular region

Molecular Function: enzyme inhibitor activity; transporter activity; calcium ion binding

Biological Process: lactation; calcium ion transport; negative regulation of catalytic activity

Research Articles on CSN2

1. Exogenous 5-HT decreased beta-casein expression in MCF-12A human mammary epithelial cells and was responsible for inhibiting phosphorylation of STAT5, resulting in a decline in lactational function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CSN2 elisa kit

Reference Product	PubMed Publications
CSN3 elisa kit	>46 publications with CSN2 and CSN3
CSN1S1 elisa kit	>38 publications with CSN2 and CSN1S1
LALBA elisa kit	>13 publications with CSN2 and LALBA
IGF2 elisa kit	>1 publications with CSN2 and IGF2
STAT3 elisa kit	>1 publications with CSN2 and STAT3
COPS5 elisa kit	>1 publications with CSN2 and COPS5

Pathways associated with CSN2 elisa kit

Products by Pathway	Pathway Diagram
Glucocorticoid Receptor Regulatory Network Pathway antibodies	Glucocorticoid Receptor Regulatory Network Pathway Diagram
Nuclear Signaling By ERBB4 Pathway antibodies	Nuclear Signaling By ERBB4 Pathway Diagram
Prolactin Signaling Pathway antibodies	Prolactin Signaling Pathway Diagram
Prolactin Signaling Pathway antibodies	Prolactin Signaling Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By ERBB4 Pathway antibodies	Signaling By ERBB4 Pathway Diagram
Signaling Events Mediated By PTP1B Pathway antibodies	Signaling Events Mediated By PTP1B Pathway Diagram

Diseases associated with CSN2 elisa kit

Disease Name	Pubmed Publications
Carcinoma Antibodies	>5 publications with CSN2 and Carcinoma
Cardiovascular Diseases Antibodies	>2 publications with CSN2 and Cardiovascular Diseases
Breast Neoplasms Antibodies	>2 publications with CSN2 and Breast Neoplasms
Inflammation Antibodies	>2 publications with CSN2 and Inflammation
Nervous System Malformations Antibodies	>2 publications with CSN2 and Nervous System Malformations
Atherosclerosis Antibodies	>1 publications with CSN2 and Atherosclerosis
Necrosis Antibodies	>1 publications with CSN2 and Necrosis
Kidney Diseases Antibodies	>1 publications with CSN2 and Kidney Diseases
Prenatal Injuries Antibodies	>1 publications with CSN2 and Prenatal Injuries
Prenatal Exposure Delayed Effects Antibodies	>1 publications with CSN2 and Prenatal Exposure Delayed Effects