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CD226 Molecule (CD226) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS911706

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CD226 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CD226 present is bound by the… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD226 molecule, ELISA Kit
Full Product Name
Human CD226 antigen, CD226 ELISA Kit
Product Gene Name
CD226 elisa kit
Product Synonym Names
Human CD226 antigen (CD226) ELISA kit; DNAM-1; DNAM1; PTA1; TLiSA1; CD226 antigen; DNAX accessory molecule-1; T lineage-specific activation antigen 1 antigen; adhesion glycoprotein; platelet and T cell activation antigen 1; CD226 molecule
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, tissue homogenates
Detection Range
0.9 ng/ml-60 ng/ml
Sensitivity
0.22 ng/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of Human CD226. No significant cross-reactivity or interference between Human CD226 and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Molecular Weight
38,614 Da
OMIM
605397
3D Structure
ModBase 3D Structure for Q15762
Detection Wavelength
450 nm
Sample Volume
50-100ul
Protein Biological Process 1
Cell Adhesion
Protein Biological Process 3
Cell adhesion
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of CD226 elisa kit

Human CD226 ELISA Kit – Cat# MBS911706

Other Notes

Small volumes of CD226 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD226 purchase

MBS911706 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD226 molecule, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CD226. The ELISA analytical biochemical technique of the MBS911706 kit is based on CD226 antibody-CD226 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD226 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD226. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CD226. It may not necessarily be applicable to this product.

NCBI GI #
171460997
NCBI GeneID
10666
NCBI Accession #
NP_006557.2
UniProt Primary Accession #
Q15762
UniProt Secondary Accession #
B2R818
UniProt Related Accession #
Q15762
GenBank Nucleotide #
NM_006566.2
NCBI Official Full Name
CD226 antigen
NCBI Official Synonym Full Names
CD226 molecule
NCBI Official Symbol
CD226
NCBI Official Synonym Symbols
PTA1; DNAM1; DNAM-1; TLiSA1
UniProt Protein Name
CD226 antigen
UniProt Synonym Protein Names
DNAX accessory molecule 1; DNAM-1; CD_antigen: CD226
Protein Family
CD226 antigen
UniProt Gene Name
CD226
UniProt Synonym Gene Names
DNAM1; DNAM-1
UniProt Entry Name
CD226_HUMAN
NCBI Protein Information
CD226 antigen; adhesion glycoprotein; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen

NCBI Summary for CD226

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD226

DNAM-1: Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 18q22.3

Cellular Component: cell surface; integral to plasma membrane; plasma membrane; external side of plasma membrane; lipid raft

Molecular Function: integrin binding; protein binding; cell adhesion molecule binding; protein kinase binding

Biological Process: regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of immunoglobulin mediated immune response; cytokine production; cell recognition; positive regulation of natural killer cell mediated cytotoxicity; signal transduction; cell adhesion; positive regulation of mast cell activation
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Research Articles on CD226

1. CD226 rs763361, but not rs727088, gene polymorphism increased the risk of rheumatoid arthritis in a sample of the Iranian population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD226 elisa kit

 Reference Product  PubMed Publications
 PVR elisa kit  >14 publications with CD226 and PVR
 FYN elisa kit  >5 publications with CD226 and FYN
 ITGB2 elisa kit  >2 publications with CD226 and ITGB2

Pathways associated with CD226 elisa kit

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram

Diseases associated with CD226 elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >42 publications with CD226 and Neoplasms
 Autoimmune Diseases Antibodies  >31 publications with CD226 and Autoimmune Diseases
 Inflammation Antibodies  >8 publications with CD226 and Inflammation
 Disease Models, Animal Antibodies  >7 publications with CD226 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >7 publications with CD226 and Cardiovascular Diseases
 Colorectal Neoplasms Antibodies  >7 publications with CD226 and Colorectal Neoplasms
 Diabetes Mellitus, Type 1 Antibodies  >6 publications with CD226 and Diabetes Mellitus, Type 1
 Breast Neoplasms Antibodies  >3 publications with CD226 and Breast Neoplasms
 Liver Neoplasms Antibodies  >2 publications with CD226 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with CD226 and Carcinoma, Hepatocellular

Organs/Tissues associated with CD226 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >99 publications with CD226 and Blood
 Vascular Antibodies  >8 publications with CD226 and Vascular
 Lung Antibodies  >6 publications with CD226 and Lung
 Lymph Node Antibodies  >5 publications with CD226 and Lymph Node
 Liver Antibodies  >5 publications with CD226 and Liver
 Thymus Antibodies  >3 publications with CD226 and Thymus
 Spleen Antibodies  >3 publications with CD226 and Spleen
 Mixed Antibodies  >2 publications with CD226 and Mixed
 Uterus Antibodies  >1 publications with CD226 and Uterus
 Kidney Antibodies  >1 publications with CD226 and Kidney
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