Galectin 3 (GAL3) ELISA Kit for Human

Name: Human GAL3 ELISA Kit; Galectin 3; MyBioSource
Brand: MyBioSource
SKU: MBS2021076
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2021076

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Galectin 3 (GAL3). Standards or samples are then added to the appropriate microtiter plate wells… More details

$405 / 24-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Galectin 3 (GAL3), ELISA Kit

Full Product Name

Human Galectin 3 (GAL3) ELISA Kit

Product Gene Name

GAL3 elisa kit

Product Synonym Names

LGALS3; CBP35; GALBP; GALIG; MAC2; 35 kDa lectin; Carbohydrate-binding protein 35; Galactose-specific lectin 3; Galactoside-binding protein; Laminin-binding protein; Lectin L-29

Species Reactivity

Human

Assay Type

Double-antibody Sandwich

Samples

Serum, Plasma, Tissue homogenates, Cell lysates, Cell culture supernates and other biological fluids

Detection Range

0.156-10ng/mL

Sensitivity

0.054ng/mL

Specificity

This assay has high sensitivity and excellent specificity for detection of Galectin 3 (GAL3).
No significant cross-reactivity or interference between Galectin 3 (GAL3) and analogues was observed.

Preparation and Storage

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Molecular Weight

26,152 Da

OMIM

153619

3D Structure

ModBase 3D Structure for P17931

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Application

Enzyme-linked immunosorbent assay for Antigen Detection.

Intra-assay Precision (Precision within an assay)

3 samples with low, middle and high level Galectin 3 (GAL3) were tested 20 times on one plate, respectively.

Inter-assay Precision (Precision between assays)

3 samples with low, middle and high level Galectin 3 (GAL3) were tested on 3 different plates, 8 replicates in each plate.

CV(%) =

SD/meanX100

Intra-Assay

CV<10%

Inter-Assay

CV<12%

Product Categories/Family for GAL3 elisa kit

Infection immunity

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of GAL3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAL3 purchase

MBS2021076 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Galectin 3 (GAL3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GAL3. The ELISA analytical biochemical technique of the MBS2021076 kit is based on GAL3 antibody-GAL3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GAL3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GAL3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GAL3. It may not necessarily be applicable to this product.

NCBI GI #

2385452

NCBI GeneID

3958

NCBI Accession #

BAA22164.1

UniProt Primary Accession #

P17931

UniProt Secondary Accession #

Q16005; Q6IBA7; Q96J47; B2RC38

UniProt Related Accession #

P17931

NCBI Official Full Name

galectin-3

NCBI Official Synonym Full Names

lectin, galactoside-binding, soluble, 3

NCBI Official Symbol

LGALS3

NCBI Official Synonym Symbols

L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2

UniProt Protein Name

Galectin-3

UniProt Synonym Protein Names

35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen

UniProt Gene Name

LGALS3

UniProt Synonym Gene Names

MAC2; Gal-3; CBP 35; GALBP

UniProt Entry Name

LEG3_HUMAN

NCBI Protein Information

galectin-3

NCBI Summary for GAL3

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]

UniProt Comments for GAL3

Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Extracellular matrix; Cell surface; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q22.3

Cellular Component: spliceosome; extracellular matrix; proteinaceous extracellular matrix; extracellular space; membrane; mitochondrial inner membrane; cytoplasm; plasma membrane; immunological synapse; nucleus; external side of plasma membrane

Molecular Function: protein binding; laminin binding; IgE binding; carbohydrate binding; chemoattractant activity

Biological Process: neutrophil chemotaxis; extracellular matrix organization and biogenesis; RNA splicing; negative regulation of endocytosis; regulation of T cell proliferation; negative regulation of T cell receptor signaling pathway; macrophage chemotaxis; monocyte chemotaxis; epithelial cell differentiation; positive chemotaxis; eosinophil chemotaxis; innate immune response; mRNA processing; skeletal development

Research Articles on GAL3

1. long-term biological variability of galectin-3 after heart transplantation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GAL3 elisa kit

Reference Product	PubMed Publications
LGALS3BP elisa kit	>39 publications with GAL3 and LGALS3BP
EGFR elisa kit	>35 publications with GAL3 and EGFR
MUC1 elisa kit	>26 publications with GAL3 and MUC1
KRAS elisa kit	>9 publications with GAL3 and KRAS
GEMIN4 elisa kit	>5 publications with GAL3 and GEMIN4
PRKCSH elisa kit	>2 publications with GAL3 and PRKCSH
NRAS elisa kit	>2 publications with GAL3 and NRAS
HRAS elisa kit	>2 publications with GAL3 and HRAS
DDOST elisa kit	>2 publications with GAL3 and DDOST
SUFU elisa kit	>1 publications with GAL3 and SUFU

Pathways associated with GAL3 elisa kit

Products by Pathway	Pathway Diagram
AGE/RAGE Pathway antibodies	AGE/RAGE Pathway Diagram
Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies	Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies	Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Spinal Cord Injury Pathway antibodies	Spinal Cord Injury Pathway Diagram

Diseases associated with GAL3 elisa kit

Disease Name	Pubmed Publications
Carcinoma Antibodies	>544 publications with GAL3 and Carcinoma
Inflammation Antibodies	>274 publications with GAL3 and Inflammation
Adenocarcinoma Antibodies	>227 publications with GAL3 and Adenocarcinoma
Fibrosis Antibodies	>161 publications with GAL3 and Fibrosis
Disease Models, Animal Antibodies	>153 publications with GAL3 and Disease Models, Animal
Neoplasm Metastasis Antibodies	>150 publications with GAL3 and Neoplasm Metastasis
Adenoma Antibodies	>137 publications with GAL3 and Adenoma
Heart Diseases Antibodies	>135 publications with GAL3 and Heart Diseases
Brain Diseases Antibodies	>114 publications with GAL3 and Brain Diseases
Breast Neoplasms Antibodies	>112 publications with GAL3 and Breast Neoplasms

Organs/Tissues associated with GAL3 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>592 publications with GAL3 and Blood
Thyroid Antibodies	>297 publications with GAL3 and Thyroid
Heart Antibodies	>208 publications with GAL3 and Heart
Vascular Antibodies	>180 publications with GAL3 and Vascular
Brain Antibodies	>152 publications with GAL3 and Brain
Kidney Antibodies	>127 publications with GAL3 and Kidney
Liver Antibodies	>126 publications with GAL3 and Liver
Lung Antibodies	>126 publications with GAL3 and Lung
Bone Antibodies	>113 publications with GAL3 and Bone
Muscle Antibodies	>93 publications with GAL3 and Muscle