Goosecoid (GSC) ELISA Kit for Human

Name: Human GSC ELISA Kit; Goosecoid; MyBioSource
Brand: MyBioSource
SKU: MBS9302100
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9302100

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of GSC (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates,… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Goosecoid (GSC), ELISA Kit

Full Product Name

Human Goosecoid (GSC) ELISA Kit

Product Gene Name

GSC elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Body fluids, tissue homogenates, secretions or feces samples

Detection Range

0.625 ng/ml - 20 ng/ml

Sensitivity

0.1 ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

28,150 Da

Chromosome Location

Chromosome: 14; NC_000014.8 (95234560..95236499, complement). Location: 14q32.1

OMIM

138890

3D Structure

ModBase 3D Structure for P56915

Other Notes

Small volumes of GSC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSC purchase

MBS9302100 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Goosecoid (GSC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GSC. The ELISA analytical biochemical technique of the MBS9302100 kit is based on GSC antibody-GSC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GSC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GSC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GSC. It may not necessarily be applicable to this product.

NCBI GI #

119602000

NCBI GeneID

145258

NCBI Accession #

EAW81594.1

UniProt Primary Accession #

P56915

UniProt Secondary Accession #

Q86YR1

UniProt Related Accession #

P56915

NCBI Official Full Name

goosecoid

NCBI Official Synonym Full Names

goosecoid homeobox

NCBI Official Symbol

GSC

UniProt Protein Name

Homeobox protein goosecoid

Protein Family

Homeobox protein

UniProt Gene Name

GSC

UniProt Entry Name

GSC_HUMAN

NCBI Protein Information

homeobox protein goosecoid

NCBI Summary for GSC

This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. [provided by RefSeq, Jul 2008]

UniProt Comments for GSC

GSC: Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring. Belongs to the paired homeobox family. Bicoid subfamily.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 14q32.1

Cellular Component: transcription factor complex; nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: neural crest cell fate specification; negative regulation of Wnt receptor signaling pathway; forebrain development; gastrulation; negative regulation of transcription from RNA polymerase II promoter; middle ear morphogenesis; muscle morphogenesis; dorsoventral neural tube patterning; embryonic skeletal morphogenesis

Disease: Short Stature, Auditory Canal Atresia, Mandibular Hypoplasia, And Skeletal Abnormalities

Research Articles on GSC

1. GSC represses EVX1 expression and is required for development of anterior primitive-streak-like cell progeny in response to activin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GSC elisa kit

Reference Product	PubMed Publications
SMAD2 elisa kit	>9 publications with GSC and SMAD2
SMAD4 elisa kit	>6 publications with GSC and SMAD4
EDN1 elisa kit	>5 publications with GSC and EDN1
FOXH1 elisa kit	>5 publications with GSC and FOXH1
RB1 elisa kit	>1 publications with GSC and RB1

Pathways associated with GSC elisa kit

Products by Pathway	Pathway Diagram
Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies	Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
Regulation Of Retinoblastoma Protein Pathway antibodies	Regulation Of Retinoblastoma Protein Pathway Diagram

Diseases associated with GSC elisa kit

Disease Name	Pubmed Publications
Craniofacial Abnormalities Antibodies	>27 publications with GSC and Craniofacial Abnormalities
Embryo Loss Antibodies	>22 publications with GSC and Embryo Loss
Cardiovascular Diseases Antibodies	>20 publications with GSC and Cardiovascular Diseases
Drug Toxicity Antibodies	>16 publications with GSC and Drug Toxicity
Abnormalities, Multiple Antibodies	>15 publications with GSC and Abnormalities, Multiple
Immune System Diseases Antibodies	>14 publications with GSC and Immune System Diseases
Necrosis Antibodies	>9 publications with GSC and Necrosis
Disease Models, Animal Antibodies	>7 publications with GSC and Disease Models, Animal
Jaw Abnormalities Antibodies	>5 publications with GSC and Jaw Abnormalities
Cognition Disorders Antibodies	>5 publications with GSC and Cognition Disorders

Organs/Tissues associated with GSC elisa kit

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>95 publications with GSC and Embryonic Tissue
Bone Antibodies	>77 publications with GSC and Bone
Connective Tissue Antibodies	>6 publications with GSC and Connective Tissue