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CD11c Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800436

CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2… More details

$310 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD11c, Antibody
Full Product Name
Anti-Hu CD11c Purified
Product Gene Name
Product Synonym Gene Name
ITGAX
Product Synonym Names
integrin subunit alpha X; Integrin alpha X; ITGAX; SLEB6
Isotype
IgG1
Clone Number
BU15
Host
Mouse
Species Reactivity
Human, Monkey
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purity/Purification
Purified by Protein-A Affinity Chromatography
Concentration
1 mg/ml (lot specific)
Specificity
The antibody BU15 reacts with an extracellular epitope of CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
Preparation and Storage
Store at 2-8 degree C.
Matching Pairs
Unconjugated Antibody: CD11c Clone #BU15 (MBS1800436)
APC Conjugated Antibody: CD11c Clone #BU15 (MBS1800437)
Matching Pairs
Unconjugated Antibody: CD11c Clone #BU15 (MBS1800436)
FITC Conjugated Antibody: CD11c Clone #BU15 (MBS1800438)
OMIM
151510
3D Structure
ModBase 3D Structure for P20702
Immunogen
Dendritic cells of synovial fluid
Applications Tested/Suitable for anti-CD11c antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) Frozen
Application Notes for anti-CD11c antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD11c antibody

Separation of human monocytes (red-filled) from CD11c negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD11c (BU15) purified antibody (concentration in sample 2 ug/ml, GAM APC).
Mouse Anti-CD11c Antibody – Cat# MBS1800436

Flow Cytometry (FC/FACS) of anti-CD11c antibody

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD11c (BU15) purified antibody (concentration in sample 2 ug/ml, GAM APC).
Mouse Anti-CD11c Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800436

Other Notes

Small volumes of anti-CD11c antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD11c purchase

MBS1800436 is an antibody targeting CD11c. Also known as Anti-Hu CD11c Purified. Reactive in Human, Monkey. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD11c. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-X isoform 2
NCBI Official Synonym Full Names
integrin subunit alpha X
NCBI Official Symbol
ITGAX
NCBI Official Synonym Symbols
CD11C; SLEB6
UniProt Protein Name
Integrin alpha-X
UniProt Synonym Protein Names
CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95
Protein Family
UniProt Gene Name
ITGAX
UniProt Synonym Gene Names
CD11C
UniProt Entry Name
ITAX_HUMAN
NCBI Protein Information
integrin alpha-X

NCBI Summary for CD11c

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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