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CLK1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS853849

MBS853849 is an antibody targeting CLK1. Also known as CLK1 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLK1, Antibody
Full Product Name
CLK1 Antibody
Product Gene Name
Product Synonym Names
CDC like kinase 1; CLK; CLK1; Dual specificity protein kinase CLK1; EC 2.7.1.112; EC 2.7.12.1
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CLK1 antibody detects endogenous levels of total CLK1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
61,757 Da
OMIM
601951
3D Structure
ModBase 3D Structure for P49759
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CLK1.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CLK1 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CLK1 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:1000

Testing Data of anti-CLK1 antibody

Anti-CLK1 Antibody – Cat# MBS853849

Western Blot (WB) of anti-CLK1 antibody

Peptide-+ Western blot analysis of extracts from 293 cells, using CLK1 antibody. Immunofluorescence analysis of HUVEC cells, using CLK1 antibody.
Anti-CLK1 Antibody, Western Blot (WB) – Cat# MBS853849

Product References and Citations for anti-CLK1 antibody

Johnson K.W., J. Biol. Chem. 266:3402-3407(1991). Hanes J.J., J. Mol. Biol. 244:665-672(1994). Olsen J.V., Cell 127:635-648(2006).

Other Notes

Small volumes of anti-CLK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CLK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dual specificity protein kinase CLK1 isoform 2
NCBI Official Synonym Full Names
CDC like kinase 1
NCBI Official Symbol
CLK1
NCBI Official Synonym Symbols
CLK; STY; CLK/STY
UniProt Protein Name
Dual specificity protein kinase CLK1
UniProt Synonym Protein Names
CDC-like kinase 1
UniProt Gene Name
CLK1
UniProt Synonym Gene Names
CLK
NCBI Protein Information
dual specificity protein kinase CLK1

NCBI Summary for CLK1

This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
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UniProt Comments for CLK1

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLK1 antibody

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