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HDAC5 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8512492

HDAC9 a transcriptional regulator of the histone deacetylase family, subfamily 2. Deacetylates lysine residues on the N-terminal part of the core histones H2A, H2B, H3 AND H4. More details

$295 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HDAC5, Antibody
Full Product Name
HDAC5 Antibody
Product Gene Name
Product Synonym Names
DKFZp779K1053; HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4/5-related protein; histone deacetylase 7; Histone deacetylase 7B; Histone deacetylase 9; Histone deacetylase-related protein; KIAA0744; MEF-2 interacti
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Immunogen affinity purified
Specificity
HDAC5 Antibody detects endogenous levels of total HDAC5
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
124kDa
OMIM
605315
3D Structure
ModBase 3D Structure for Q9UQL6
Immunogen
A synthesized peptide derived from human HDAC5
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HDAC5 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-HDAC5 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-HDAC5 antibody

Western blot analysis of HDAC5 expression in HepG2 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.
Anti-HDAC5 Antibody – Cat# MBS8512492

Other Notes

Small volumes of anti-HDAC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HDAC5 purchase

MBS8512492 is an antibody targeting HDAC5. Also known as HDAC5 Antibody. Reactive in Human, Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HDAC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
histone deacetylase 5 isoform 3
NCBI Official Synonym Full Names
histone deacetylase 5
NCBI Official Symbol
HDAC5
NCBI Official Synonym Symbols
HD5; NY-CO-9
UniProt Protein Name
Histone deacetylase 5
UniProt Synonym Protein Names
Antigen NY-CO-9
UniProt Gene Name
HDAC5
UniProt Synonym Gene Names
KIAA0600; HD5
NCBI Protein Information
histone deacetylase 5

NCBI Summary for HDAC5

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for HDAC5

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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