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STAT4 Blocking Peptide – >85% Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8244467

MBS8244467 is a blocking peptide targeting STAT4. Reactive in Human, Mouse. Host: Synthetic. The peptide is used to block Anti-STAT4 Antibody reactivity. More details

$230 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STAT4, Blocking Peptide
Full Product Name
STAT4 Blocking Peptide
Product Gene Name
Product Synonym Names
Signal transducer and activator of transcription 4
Host
Synthetic
Species Reactivity
Human, Mouse
Form/Format
Lyophilized Powder
Purity/Purification
>85%
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Antibody/Peptide Pairs
STAT4 peptide (MBS8244467) is used for blocking the activity of STAT4 antibody (MBS8242064)
Molecular Weight
85,941 Da
OMIM
180300
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Applications Tested/Suitable for STAT4 blocking peptide
Blocking (BL)
Application Notes for STAT4 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Other Notes

Small volumes of STAT4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STAT4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Signal transducer and activator of transcription 4
NCBI Official Synonym Full Names
signal transducer and activator of transcription 4
NCBI Official Symbol
STAT4
NCBI Official Synonym Symbols
SLEB11
UniProt Protein Name
Signal transducer and activator of transcription 4
UniProt Gene Name
STAT4
UniProt Entry Name
STAT4_HUMAN
NCBI Protein Information
signal transducer and activator of transcription 4

NCBI Summary for STAT4

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
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UniProt Comments for STAT4

STAT4: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2q32.2-q32.3

Cellular Component: cytoplasm; nucleoplasm

Molecular Function: protein binding; transcription factor activity

Biological Process: cell proliferation; cytokine and chemokine mediated signaling pathway; JAK-STAT cascade; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; transcription, DNA-dependent

Disease: Systemic Lupus Erythematosus, Susceptibility To, 11
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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