• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CREB Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857584

MBS857584 is an antibody targeting CREB. Also known as CREB (Ab-129) Antibody. Reactive in Human, Mouse, Rat. More details

$235 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CREB, Antibody
Full Product Name
CREB (Ab-129) Antibody
Product Gene Name
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CREB (Ab-129) antibody detects endogenous levels of total CREB protein.
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
25,445 Da
OMIM
123810
3D Structure
ModBase 3D Structure for P16220
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 (I-L-SP-R-R).
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CREB antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CREB antibody
WB: 1:500~1:1000
IHC: 1:50~1:100

Immunohistochemistry (IHC) of anti-CREB antibody

Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB (Ab-129) antibody.
Anti-CREB Antibody – Cat# MBS857584

Western Blot (WB) of anti-CREB antibody

Western blot analysis of extracts from 293 cells untreated or treated with UV, using CREB (Ab-129) antibody and CREB (phospho-Ser129) antibody.
Anti-CREB Antibody, Western Blot (WB) – Cat# MBS857584

Product References and Citations for anti-CREB antibody

Chrystelle V. Garat, et al. (2006) Mol. Cell. Biol; 26: 4934-4948. Lilah Rothem, et al. (2004) Mol. Pharmacol; 66: 1536-1543. Darren R. Tyson, et, al. (2002) Endocrinology; 143: 674. Kyung-Woo Park, et al. (2003) Arterioscler. Thromb. Vasc. Biol; 23: 1364.

Other Notes

Small volumes of anti-CREB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CREB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclic AMP-responsive element-binding protein 1 isoform A
NCBI Official Synonym Full Names
cAMP responsive element binding protein 1
NCBI Official Symbol
CREB1
NCBI Official Synonym Symbols
CREB; CREB-1
UniProt Protein Name
Cyclic AMP-responsive element-binding protein 1
UniProt Gene Name
CREB1
UniProt Synonym Gene Names
CREB-1; cAMP-responsive element-binding protein 1
NCBI Protein Information
cyclic AMP-responsive element-binding protein 1

NCBI Summary for CREB

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Show more

UniProt Comments for CREB

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000