CHAC1 Blocking Peptide – >85% Purity

Name: CHAC1 Blocking Peptide; >85% Purity; MyBioSource
Brand: MyBioSource
SKU: MBS824337
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824337

MBS824337 is a blocking peptide targeting CHAC1. Reactive in Human, Mouse, Rat. Host: Synthetic. The peptide is used to block Anti-CHAC1 Antibody reactivity. More details

$230 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CHAC1, Blocking Peptide

Full Product Name

CHAC1 Blocking Peptide

Product Gene Name

CHAC1 blocking peptide

Product Synonym Names

BOTCH; Cation transport regulator-like protein 1; Blocks Notch protein; Botch

Host

Synthetic

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized powder

Purity/Purification

>85%

Preparation and Storage

Shipped at 4 degree C. Store at -20 degree C for one year.

Antibody/Peptide Pairs

CHAC1 peptide (MBS824337) is used for blocking the activity of CHAC1 antibody (MBS820290)

Molecular Weight

23,795 Da

OMIM

614587

Quality Control

The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

Applications Tested/Suitable for CHAC1 blocking peptide

Blocking (BL)

Application Notes for CHAC1 blocking peptide

Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Other Notes

Small volumes of CHAC1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHAC1. It may not necessarily be applicable to this product.

NCBI GI #

218563700

NCBI GeneID

79094

NCBI Accession #

NP_001136248.1

UniProt Primary Accession #

Q9BUX1

UniProt Secondary Accession #

Q0VIA0

UniProt Related Accession #

Q9BUX1

GenBank Nucleotide #

NM_001142776.1

NCBI Official Full Name

cation transport regulator-like protein 1 isoform b

NCBI Official Synonym Full Names

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

NCBI Official Symbol

CHAC1

UniProt Protein Name

Cation transport regulator-like protein 1

UniProt Synonym Protein Names

Blocks Notch protein; Botch

Protein Family

Glutathione-specific gamma-glutamylcyclotransferase

UniProt Gene Name

CHAC1

UniProt Synonym Gene Names

BOTCH; Botch

UniProt Entry Name

CHAC1_HUMAN

NCBI Protein Information

cation transport regulator-like protein 1; botch; blocks Notch protein; ChaC, cation transport regulator-like 1; gamma-GCT acting on glutathione homolog 1; ChaC, cation transport regulator homolog 1

UniProt Comments for CHAC1

CHAC1: Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Belongs to the chaC family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: trans-Golgi network; cytosol

Molecular Function: protein binding; transferase activity, transferring acyl groups; Notch binding

Biological Process: Notch signaling pathway; neurogenesis; metabolic process; negative regulation of Notch signaling pathway; response to unfolded protein

Research Articles on CHAC1

1. nisin exerts these effects on HNSCC, in part, through CHAC1, a proapoptotic cation transport regulator, and through a concomitant CHAC1-independent influx of extracellular calcium

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with CHAC1 blocking peptide

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>2 publications with CHAC1 and Breast Neoplasms
Liver Diseases Antibodies	>2 publications with CHAC1 and Liver Diseases
Necrosis Antibodies	>2 publications with CHAC1 and Necrosis
Inflammation Antibodies	>1 publications with CHAC1 and Inflammation

Organs/Tissues associated with CHAC1 blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>2 publications with CHAC1 and Liver
Eye Antibodies	>1 publications with CHAC1 and Eye
Muscle Antibodies	>1 publications with CHAC1 and Muscle
Brain Antibodies	>1 publications with CHAC1 and Brain