MPZ Blocking Peptide – >85% Purity

Name: MPZ Blocking Peptide; >85% Purity; MyBioSource
Brand: MyBioSource
SKU: MBS823417
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS823417

MBS823417 is a blocking peptide targeting MPZ. Reactive in Human, Mouse, Rat. Host: Synthetic. The peptide is used to block Anti-MPZ Antibody reactivity. More details

$230 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MPZ, Blocking Peptide

Full Product Name

MPZ Blocking Peptide

Product Gene Name

MPZ blocking peptide

Product Synonym Names

Myelin protein P0; Myelin peripheral protein; MPP; Myelin protein zero

Host

Synthetic

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized powder

Purity/Purification

>85%

Preparation and Storage

Shipped at 4 degree C. Store at -20 degree C for one year.

Antibody/Peptide Pairs

MPZ peptide (MBS823417) is used for blocking the activity of MPZ antibody (MBS821236)

Molecular Weight

34,387 Da

OMIM

phenotype 607791

Quality Control

The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

Applications Tested/Suitable for MPZ blocking peptide

Blocking (BL)

Application Notes for MPZ blocking peptide

Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Other Notes

Small volumes of MPZ blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MPZ. It may not necessarily be applicable to this product.

NCBI GI #

295391071

NCBI GeneID

4359

NCBI Accession #

NP_000521.2

UniProt Primary Accession #

P25189

UniProt Secondary Accession #

Q16072; Q5VTH4; Q92677; Q9BR67

UniProt Related Accession #

P25189

GenBank Nucleotide #

NM_000530.6

NCBI Official Full Name

myelin protein P0

NCBI Official Synonym Full Names

myelin protein zero

NCBI Official Symbol

MPZ

NCBI Official Synonym Symbols

P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB

UniProt Protein Name

Myelin protein P0

UniProt Synonym Protein Names

Myelin peripheral protein; MPP; Myelin protein zero

Protein Family

Myelin protein

UniProt Gene Name

MPZ

UniProt Synonym Gene Names

MPP

UniProt Entry Name

MYP0_HUMAN

NCBI Protein Information

myelin protein P0; myelin peripheral protein; Charcot-Marie-Tooth neuropathy 1B

NCBI Summary for MPZ

This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. [provided by RefSeq, Apr 2010]

UniProt Comments for MPZ

myelin P0: a structural protein in peripheral nervous system Schwann cells. Forms an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae. Defects cause of Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, congenital hypomyelination neuropathy, and Roussy-Levy syndrome.

Protein type: Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: integral to plasma membrane; plasma membrane; myelin sheath

Molecular Function: structural molecule activity

Biological Process: synaptic transmission; intercellular junction maintenance

Disease: Neuropathy, Congenital Hypomyelinating Or Amyelinating, Autosomal Recessive; Charcot-marie-tooth Disease, Demyelinating, Type 1b; Hypertrophic Neuropathy Of Dejerine-sottas; Charcot-marie-tooth Disease, Dominant Intermediate D; Charcot-marie-tooth Disease, Axonal, Type 2j; Charcot-marie-tooth Disease, Axonal, Type 2i; Roussy-levy Hereditary Areflexic Dystasia

Research Articles on MPZ

1. This study demonistrated that The mutation c.419C>G of MPZ exhibited relatively late onset and slowly progressive CMT1 phenotype.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MPZ blocking peptide

Reference Product	PubMed Publications
PMP22 blocking peptide	>118 publications with MPZ and PMP22
EGR2 blocking peptide	>57 publications with MPZ and EGR2
GJB1 blocking peptide	>52 publications with MPZ and GJB1
GDAP1 blocking peptide	>17 publications with MPZ and GDAP1
SOX10 blocking peptide	>16 publications with MPZ and SOX10
PRX blocking peptide	>13 publications with MPZ and PRX
HSPB8 blocking peptide	>5 publications with MPZ and HSPB8
KIF1B blocking peptide	>5 publications with MPZ and KIF1B
MED25 blocking peptide	>2 publications with MPZ and MED25
NRG1 blocking peptide	>1 publications with MPZ and NRG1

Pathways associated with MPZ blocking peptide

Products by Pathway	Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Neural Crest Differentiation Pathway antibodies	Neural Crest Differentiation Pathway Diagram

Diseases associated with MPZ blocking peptide

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>248 publications with MPZ and Nervous System Diseases
Peripheral Nervous System Diseases Antibodies	>228 publications with MPZ and Peripheral Nervous System Diseases
Charcot-Marie-Tooth Disease Antibodies	>213 publications with MPZ and Charcot-Marie-Tooth Disease
Hereditary Sensory and Motor Neuropathy Antibodies	>210 publications with MPZ and Hereditary Sensory and Motor Neuropathy
Demyelinating Diseases Antibodies	>62 publications with MPZ and Demyelinating Diseases
Disease Models, Animal Antibodies	>19 publications with MPZ and Disease Models, Animal
Nerve Degeneration Antibodies	>14 publications with MPZ and Nerve Degeneration
Hypertrophy Antibodies	>5 publications with MPZ and Hypertrophy
Charcot-Marie-Tooth disease, Type 4E Antibodies	>3 publications with MPZ and Charcot-Marie-Tooth disease, Type 4E
Somatosensory Disorders Antibodies	>3 publications with MPZ and Somatosensory Disorders

Organs/Tissues associated with MPZ blocking peptide

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>170 publications with MPZ and Nerve
Muscle Antibodies	>50 publications with MPZ and Muscle
Brain Antibodies	>37 publications with MPZ and Brain
Blood Antibodies	>22 publications with MPZ and Blood
Skin Antibodies	>6 publications with MPZ and Skin
Embryonic Tissue Antibodies	>5 publications with MPZ and Embryonic Tissue
Eye Antibodies	>5 publications with MPZ and Eye
Heart Antibodies	>4 publications with MPZ and Heart
Pituitary Gland Antibodies	>4 publications with MPZ and Pituitary Gland
Ear Antibodies	>4 publications with MPZ and Ear