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PDE4C Blocking Peptide – >85% Purity

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS822650

MBS822650 is a blocking peptide targeting PDE4C. Reactive in Human, Mouse, Rat. Host: Synthetic. The peptide is used to block Anti-PDE4C Antibody reactivity. More details

$230 / 1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDE4C, Blocking Peptide
Full Product Name
PDE4C Blocking Peptide
Product Gene Name
Product Synonym Names
DPDE1; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21
Host
Synthetic
Species Reactivity
Human, Mouse, Rat
Form/Format
Lyophilized powder
Purity/Purification
>85%
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Antibody/Peptide Pairs
PDE4C peptide (MBS822650) is used for blocking the activity of PDE4C antibody (MBS822076)
Molecular Weight
– Da
OMIM
600128
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Applications Tested/Suitable for PDE4C blocking peptide
Blocking (BL)
Application Notes for PDE4C blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Other Notes

Small volumes of PDE4C blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDE4C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform PDE4C1
NCBI Official Synonym Full Names
phosphodiesterase 4C, cAMP-specific
NCBI Official Symbol
PDE4C
NCBI Official Synonym Symbols
DPDE1
UniProt Protein Name
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
UniProt Synonym Protein Names
DPDE1; PDE21
UniProt Gene Name
PDE4C
UniProt Synonym Gene Names
DPDE1
UniProt Entry Name
PDE4C_HUMAN
NCBI Protein Information
cAMP-specific 3',5'-cyclic phosphodiesterase 4C; PDE21; phosphodiesterase E1 dunce homolog; phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)

NCBI Summary for PDE4C

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
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UniProt Comments for PDE4C

PDE4C: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Phosphodiesterase; Nucleotide Metabolism - purine; EC 3.1.4.53

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: extracellular space; cytosol

Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; metal ion binding

Biological Process: cAMP catabolic process; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PDE4C blocking peptide

 Reference Product  PubMed Publications
 GNAS blocking peptide  >1 publications with PDE4C and GNAS
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