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IP3KA ELISA Kit for Human, Mouse, Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9500724

MBS9500724 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IP3KA, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

$485 / 1 Kit +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IP3KA, ELISA Kit
Full Product Name
IP3KA Colorimetric Cell-Based ELISA Kit
Product Gene Name
IP3KA elisa kit
Product Synonym Gene Name
ITPKA
Product Synonym Names
Inositol-trisphosphate 3-kinase A; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A ; ITPKA
Species Reactivity
Human, Mouse, Rat
Assay Type
Non-Phospho Cell-Based ELISA
Samples
Researchers plate their cell line of choice
Sensitivity
>=5000 cells/well
Form/Format
One 96-Well Plate
Preparation and Storage
Store at 4 degree C.
Molecular Weight
51 kDa
OMIM
X54938 mRNA
3D Structure
ModBase 3D Structure for P23677
Detection Method
Colorimetric 450 nm

Product Categories/Family for IP3KA elisa kit

Cell Based ELISA Kit

Other Notes

Small volumes of IP3KA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IP3KA. It may not necessarily be applicable to this product.

NCBI GI #
4504789
NCBI GeneID
3706
NCBI Accession #
NP_002211.1
UniProt Primary Accession #
P23677
UniProt Secondary Accession #
Q8TAN3
UniProt Related Accession #
P23677
GenBank Nucleotide #
NM_002220.2
NCBI Official Full Name
inositol-trisphosphate 3-kinase A
NCBI Official Synonym Full Names
inositol-trisphosphate 3-kinase A
NCBI Official Symbol
ITPKA
NCBI Official Synonym Symbols
IP3KA; IP3-3KA
UniProt Protein Name
Inositol-trisphosphate 3-kinase A
UniProt Synonym Protein Names
Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A
UniProt Gene Name
ITPKA
UniProt Synonym Gene Names
IP3 3-kinase A; IP3K A; InsP 3-kinase A
NCBI Protein Information
inositol-trisphosphate 3-kinase A

NCBI Summary for IP3KA

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]
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UniProt Comments for IP3KA

ITPKA: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.127; Kinase, lipid; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: cytosol; dendritic spine

Molecular Function: ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; inositol trisphosphate 3-kinase activity; Rac GTPase binding

Biological Process: actin cytoskeleton organization; inositol metabolic process; inositol phosphate biosynthetic process; inositol phosphate metabolic process; protein amino acid phosphorylation; regulation of synaptic plasticity; signal transduction
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Research Articles on IP3KA

1. Our data indicated that ITPKA expression was significantly up-regulated in hepatocellular carcinoma and could serve as a potential novel prognostic biomarker

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IP3KA elisa kit

 Products by Pathway  Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,3,4)-trisphosphate Biosynthesis Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram

Diseases associated with IP3KA elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with IP3KA and Neoplasms
 Disease Models, Animal Antibodies  >1 publications with IP3KA and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >1 publications with IP3KA and Neoplasms, Experimental
 Weight Loss Antibodies  >1 publications with IP3KA and Weight Loss

Organs/Tissues associated with IP3KA elisa kit

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >2 publications with IP3KA and Ovary
 Lung Antibodies  >2 publications with IP3KA and Lung
 Brain Antibodies  >2 publications with IP3KA and Brain
 Testis Antibodies  >1 publications with IP3KA and Testis
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