• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CD105 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1801123

CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide… More details

$345 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD105, Antibody
Full Product Name
Anti-Hu CD105 Biotin
Product Gene Name
Product Synonym Gene Name
ENG
Product Synonym Names
endoglin; Endoglin; END; ENG; HHT1; ORW1
Isotype
IgG2a
Clone Number
MEM-229
Host
Mouse
Species Reactivity
Pig, Human
Form/Format
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Purity/Purification
The purified antibody is conjugated with biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Concentration
1 mg/ml (lot specific)
Specificity
The antibody MEM-229 recognizes an extracellular epitope of CD105 (Endoglin), a 90 kDa type I integral membrane homodimer glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy.
Preparation and Storage
Store at 2-8 degree C.
Matching Pairs
Unconjugated Antibody: CD105 Clone #MEM-229 (MBS1801122)
Biotin Conjugated Antibody: CD105 Clone #MEM-229 (MBS1801123)
OMIM
131195
3D Structure
ModBase 3D Structure for P17813
Immunogen
Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.
Negative Species
Dog, Horse
Conjugation
Biotin
Applications Tested/Suitable for anti-CD105 antibody
Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC) Frozen, Immunocytochemistry (ICC)
Application Notes for anti-CD105 antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD105 antibody

Flow cytometry analysis (surface staining) of CD105 on Huvec and HEK-293 cells with anti-CD105 (MEM-229) biotin.
Mouse Anti-CD105 Antibody – Cat# MBS1801123

Other Notes

Small volumes of anti-CD105 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD105 purchase

MBS1801123 is an antibody targeting CD105. Also known as Anti-Hu CD105 Biotin. Reactive in Pig, Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD105. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endoglin isoform 2
NCBI Official Synonym Full Names
endoglin
NCBI Official Symbol
ENG
NCBI Official Synonym Symbols
END; HHT1; ORW1
UniProt Protein Name
Endoglin
Protein Family
UniProt Gene Name
ENG
UniProt Synonym Gene Names
END
UniProt Entry Name
EGLN_HUMAN
NCBI Protein Information
endoglin

NCBI Summary for CD105

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000