Rat MIP-1beta Active Protein – Cat# MBS696068

MIP-1beta Rat Active Protein

Name: MIP-1beta Active Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS696068
Price: 180 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS696068

Both MIP-1 alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

MIP-1beta, Active Protein

Full Product Name

Rat MIP-1beta (CCL4)

Product Gene Name

MIP-1beta active protein

Product Synonym Gene Name

CCL4

Product Synonym Names

Recombinant Rat MIP-1beta (CCL4)

Sequence

APIGSDPPT SCCFSYTSR KIHRNFVMD YYETSSLCS QPAVVFLTK KGRQICADP SEPWVNEYV NDLELN

Host

E Coli

Species Reactivity

Species Reactivity: Rat
Cross Reactivity: Human

Purity/Purification

Above 98% as determined by SDS-PAGE Analysis.

Preparation and Storage

At -20 degree C

Molecular Weight

10,234 Da

3D Structure

ModBase 3D Structure for P50230

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Determined by its ability to chemoattract human monocytes using a concentration range of 0.01-1.0 ug/ml.

Cell Type

Monocytes and Macrophages, NK and NKT Cells

Product Categories/Family for MIP-1beta active protein

Innate Immunity; Neurosciences; Inflammation; Chemotaxis

Other Notes

Small volumes of MIP-1beta active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIP-1beta purchase

MBS696068 is an active protein targeting MIP-1beta. Also known as Rat MIP-1beta (CCL4). Reactive in Species Reactivity: Rat
Cross Reactivity: Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MIP-1beta. It may not necessarily be applicable to this product.

NCBI GI #

1709025

NCBI GeneID

116637

NCBI Accession #

P50230.1

UniProt Primary Accession #

P50230

UniProt Secondary Accession #

A1EC89

UniProt Related Accession #

P50230

NCBI Official Full Name

C-C motif chemokine 4

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 4

NCBI Official Symbol

Ccl4

NCBI Official Synonym Symbols

Scya4; Mip1-b

UniProt Protein Name

C-C motif chemokine 4

UniProt Synonym Protein Names

Macrophage inflammatory protein 1-beta; MIP-1-beta; Small-inducible cytokine A4

UniProt Gene Name

Ccl4

UniProt Synonym Gene Names

Mip1b; Scya4; MIP-1-beta

UniProt Entry Name

CCL4_RAT

NCBI Protein Information

C-C motif chemokine 4; MIP-1-beta; small inducible cytokine A4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta

NCBI Summary for MIP-1beta

a cytokine that is up-regulated during the inflammatory response; may be involved in intrapulmonary recruitment of neutrophils [RGD, Feb 2006]

UniProt Comments for MIP-1beta

Monokine with inflammatory and chemokinetic properties.

Research Articles on MIP-1beta

1. Tong Luo Jiu Nao injection inhibits MIP-1beta expression in brain microvascular endothelial cells injured by oxygen-glucose deprivation and inhibitors microglial cell proliferation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MIP-1beta active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
NF-kappa B Signaling Pathway antibodies	NF-kappa B Signaling Pathway Diagram

Diseases associated with MIP-1beta active protein

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>2606 publications with MIP-1beta and Liver Diseases
Poisoning Antibodies	>1973 publications with MIP-1beta and Poisoning
Drug-Induced Liver Injury Antibodies	>1578 publications with MIP-1beta and Drug-Induced Liver Injury
Disease Models, Animal Antibodies	>1268 publications with MIP-1beta and Disease Models, Animal
Necrosis Antibodies	>1201 publications with MIP-1beta and Necrosis
Drug-Related Side Effects and Adverse Reactions Antibodies	>1169 publications with MIP-1beta and Drug-Related Side Effects and Adverse Reactions
Liver Cirrhosis Antibodies	>1136 publications with MIP-1beta and Liver Cirrhosis
Inflammation Antibodies	>1080 publications with MIP-1beta and Inflammation
Fibrosis Antibodies	>928 publications with MIP-1beta and Fibrosis
Fatty Liver Antibodies	>287 publications with MIP-1beta and Fatty Liver

Organs/Tissues associated with MIP-1beta active protein

Organ/Tissue Name	Pubmed Publications
Mixed Antibodies	>161 publications with MIP-1beta and Mixed
Eye Antibodies	>61 publications with MIP-1beta and Eye