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IDI2 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8249190

Recombinant Human IDI2 Protein is produced by our E Coli expression system and the target gene encoding Met1-Val227 is expressed with a 6His tag at the N-terminus. More details

$355 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IDI2, Recombinant Protein
Full Product Name
Recombinant Human IDI2 Protein
Product Gene Name
Product Synonym Names
Isopentenyl-diphosphate delta-isomerase 2; Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2
Sequence
MGSSHHHHHH SSGLVPRGSH MSDINLDWVD RRQLQRLEEM LIVVDENDKV IGADTKRNCH LNENIEKGLL HRAFSVVLFN TKNRILIQQR SDTKVTFPGY FTDSCSSHPL YNPAELEEKD AIGVRRAAQR RLQAELGIPG EQISPEDIVF MTIYHHKAKS DRIWGEHEIC YLLLVRKNVT LNPDPSETKS ILYLSQEELW ELLEREARGE VKVTPWLRTI AERFLYRWWP HLDDVTPFVE LHKIHRV
Host
E Coli
Species Reactivity
Human
Form/Format
Supplied as a 0.2 muM filtered solution of 20mM Tris-HCl, 1mM DTT, 0.1mM PMSF, pH 8.0.
Purity/Purification
Greater than 95% as determined by reducing SDS-PAGE.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Molecular Weight
26,753 Da
OMIM
AF291755 Genomic DNA
3D Structure
ModBase 3D Structure for Q9BXS1
Endotoxin
Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Applications Tested/Suitable for IDI2 recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)

Other Notes

Small volumes of IDI2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IDI2 purchase

MBS8249190 is a recombinant protein targeting IDI2. Also known as Recombinant Human IDI2 Protein. Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for IDI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
isopentenyl-diphosphate delta-isomerase 2
NCBI Official Synonym Full Names
isopentenyl-diphosphate delta isomerase 2
NCBI Official Symbol
IDI2
NCBI Official Synonym Symbols
IPPI2
UniProt Protein Name
Isopentenyl-diphosphate delta-isomerase 2
UniProt Synonym Protein Names
Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2
UniProt Gene Name
IDI2
UniProt Synonym Gene Names
IPP isomerase 2; IPPI2
UniProt Entry Name
IDI2_HUMAN
NCBI Protein Information
isopentenyl-diphosphate delta-isomerase 2

NCBI Summary for IDI2

The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2016]
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UniProt Comments for IDI2

IDI2: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). Belongs to the IPP isomerase type 1 family.

Protein type: EC 5.3.3.2; Isomerase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis

Chromosomal Location of Human Ortholog: 10p15.3

Cellular Component: cytosol; peroxisome

Molecular Function: isopentenyl-diphosphate delta-isomerase activity

Biological Process: cholesterol biosynthetic process; isopentenyl diphosphate biosynthetic process; isopentenyl diphosphate metabolic process; isoprenoid biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IDI2 recombinant protein

Organs/Tissues associated with IDI2 recombinant protein

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