Human LSAMP Recombinant Protein – Cat# MBS8249407

LSAMP Human Recombinant Protein

Name: LSAMP Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS8249407
Price: 285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8249407

Recombinant Human LSAMP Protein is produced by our mammalian expression system and the target gene encoding Val29-Asn315 is expressed with a 6His tag at the C-terminus. More details

$285 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LSAMP, Recombinant Protein

Full Product Name

Recombinant Human LSAMP Protein

Product Gene Name

LSAMP recombinant protein

Product Synonym Names

IGLON3; LAMP; Limbic system-associated membrane protein; LSAMP; IgLON family member 3

Sequence

VRSVDFNRGT DNITVRQGDT AILRCVVEDK NSKVAWLNRS GIIFAGHDKW SLDPRVELEK RHSLEYSLRI QKVDVYDEGS YTCSVQTQHE PKTSQVYLIV QVPPKISNIS SDVTVNEGSN VTLVCMANGR PEPVITWRHL TPTGREFEGE EEYLEILGIT REQSGKYECK AANEVSSADV KQVKVTVNYP PTITESKSNE ATTGRQASLK CEASAVPAPD FEWYRDDTRI NSANGLEIKS TEGQSSLTVT NVTEEHYGNY TCVAANKLGV TNASLVLFRP GSVRGINVDH HHHHH

Host

Human cells

Species Reactivity

Human

Form/Format

Lyophilized from a 0.2 uM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Purity/Purification

>95% as determined by reducing SDS-PAGE.

Preparation and Storage

Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.

OMIM

U41901 mRNA

3D Structure

ModBase 3D Structure for Q13449

Endotoxin

< 0.1 ng/mug (1 IEU/ug) as determined by LAL test.

Directions for Use

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Applications Tested/Suitable for LSAMP recombinant protein

ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)

Other Notes

Small volumes of LSAMP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LSAMP purchase

MBS8249407 is a recombinant protein targeting LSAMP. Also known as Recombinant Human LSAMP Protein. Reactive in Human. Host: Human cells.

Additional Details

NCBI/Uniprot data below describe general gene information for LSAMP. It may not necessarily be applicable to this product.

NCBI GI #

974576775

NCBI GeneID

4045

NCBI Accession #

NP_001305844.1

UniProt Primary Accession #

Q13449

UniProt Secondary Accession #

Q8IV49

UniProt Related Accession #

Q13449

GenBank Nucleotide #

NM_001318915.1

NCBI Official Full Name

limbic system-associated membrane protein isoform 2

NCBI Official Synonym Full Names

limbic system-associated membrane protein

NCBI Official Symbol

LSAMP

NCBI Official Synonym Symbols

LAMP; IGLON3

UniProt Protein Name

Limbic system-associated membrane protein

UniProt Synonym Protein Names

IgLON family member 3

UniProt Gene Name

LSAMP

UniProt Synonym Gene Names

IGLON3; LAMP; LSAMP

UniProt Entry Name

LSAMP_HUMAN

NCBI Protein Information

limbic system-associated membrane protein

NCBI Summary for LSAMP

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

UniProt Comments for LSAMP

LSAMP: Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection. Belongs to the immunoglobulin superfamily. IgLON family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 3q13.2-q21

Molecular Function: protein binding

Biological Process: nervous system development

Research Articles on LSAMP

1. A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with LSAMP recombinant protein

Products by Pathway	Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies	Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram

Diseases associated with LSAMP recombinant protein

Disease Name	Pubmed Publications
Chromosome Aberrations Antibodies	>6 publications with LSAMP and Chromosome Aberrations
Learning Disorders Antibodies	>4 publications with LSAMP and Learning Disorders
Depressive Disorder Antibodies	>3 publications with LSAMP and Depressive Disorder
Nervous System Diseases Antibodies	>3 publications with LSAMP and Nervous System Diseases
Atherosclerosis Antibodies	>2 publications with LSAMP and Atherosclerosis
Disease Models, Animal Antibodies	>2 publications with LSAMP and Disease Models, Animal
Abnormalities, Multiple Antibodies	>2 publications with LSAMP and Abnormalities, Multiple
Lung Diseases Antibodies	>1 publications with LSAMP and Lung Diseases
Neoplasms, Experimental Antibodies	>1 publications with LSAMP and Neoplasms, Experimental
Adenocarcinoma Antibodies	>1 publications with LSAMP and Adenocarcinoma

Organs/Tissues associated with LSAMP recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>18 publications with LSAMP and Brain
Bone Antibodies	>5 publications with LSAMP and Bone
Nerve Antibodies	>5 publications with LSAMP and Nerve
Heart Antibodies	>3 publications with LSAMP and Heart
Blood Antibodies	>3 publications with LSAMP and Blood
Muscle Antibodies	>2 publications with LSAMP and Muscle
Prostate Antibodies	>2 publications with LSAMP and Prostate
Testis Antibodies	>1 publications with LSAMP and Testis
Lung Antibodies	>1 publications with LSAMP and Lung