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PPCDC Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8249622

Recombinant Human PPCDC Protein is produced by our E.coli expression system and the target gene encoding Met1-Ser204 is expressed with a 6His tag at the N-terminus. More details

$355 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PPCDC, Recombinant Protein
Full Product Name
Recombinant Human PPCDC Protein
Product Gene Name
Product Synonym Names
COAC; Phosphopantothenoylcysteine decarboxylase; PPC-DC; CoaC
Sequence
MGSSHHHHHH SSGLVPRGSH MEPKASCPAA APLMERKFHV LVGVTGSVAA LKLPLLVSKL LDIPGLEVAV VTTERAKHFY SPQDIPVTLY SDADEWEMWK SRSDPVLHID LRRWADLLLV APLDANTLGK VASGICDNLL TCVMRAWDRS KPLLFCPAMN TAMWEHPITA QQVDQLKAFG YVEIPCVAKK LVCGDEGLGA MAEVGTIVDK VKEVLFQHSG FQQS
Host
E Coli
Species Reactivity
Human
Form/Format
Supplied as a 0.2 muM filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0.
Purity/Purification
Greater than 95% as determined by reducing SDS-PAGE.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Molecular Weight
14,069 Da
OMIM
AF182419 mRNA
3D Structure
ModBase 3D Structure for Q96CD2
Endotoxin
Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Applications Tested/Suitable for PPCDC recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)

Other Notes

Small volumes of PPCDC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPCDC purchase

MBS8249622 is a recombinant protein targeting PPCDC. Also known as Recombinant Human PPCDC Protein. Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PPCDC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosphopantothenoylcysteine decarboxylase isoform b
NCBI Official Synonym Full Names
phosphopantothenoylcysteine decarboxylase
NCBI Official Symbol
PPCDC
NCBI Official Synonym Symbols
coaC; MDS018; PPC-DC
UniProt Protein Name
Phosphopantothenoylcysteine decarboxylase
UniProt Synonym Protein Names
CoaC
UniProt Gene Name
PPCDC
UniProt Synonym Gene Names
COAC; PPC-DC
UniProt Entry Name
COAC_HUMAN
NCBI Protein Information
phosphopantothenoylcysteine decarboxylase

NCBI Summary for PPCDC

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]
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UniProt Comments for PPCDC

PPCDC: Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'- phosphopantotheine. Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 4.1.1.36; Lyase

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: cytosol

Molecular Function: identical protein binding; phosphopantothenoylcysteine decarboxylase activity; protein binding

Biological Process: coenzyme A biosynthetic process; coenzyme biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PPCDC recombinant protein

 Reference Product  PubMed Publications
 PPCS recombinant protein  >2 publications with PPCDC and PPCS

Organs/Tissues associated with PPCDC recombinant protein

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