Human IL17D Active Protein – Cat# MBS140979

Interleukin-17d (IL17D) Human Active Protein

Name: IL17D Active Protein; Interleukin-17d; Human; MyBioSource
Brand: MyBioSource
SKU: MBS140979
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS140979

Introduction: IL17D modulates immune responses indirectly by stimulating the production of myeloid growth factors and chemokines, as well as suppressing the proliferation of myeloid progenitors. IL17D is expressed in the skeletal muscle, heart, adipose… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Interleukin-17D (IL17D), Active Protein

Full Product Name

Recombinant Human Interleukin-17D

Product Gene Name

IL17D active protein

Product Synonym Names

IL17D Human; Interleukin-17D Human Recombinant; Interleukin 17D; Interleukin 27; IL-17D; IL-27; IL27; Interleukin-17D; Interleukin-27; IL17D

Sequence

APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPREQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR YLPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRSVYT EAYVTIPVGC TCVPEPEKDA DSINSSIDKQ GAKLLLGPND APAGP

Host

E Coli

Form/Format

Lyophilized from a 0.2 um filtered solution in Acetonitrile and TFA.
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 97.0% as determined by SDS-PAGE.

Preparation and Storage

Lyophilized IL17D although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL-17D should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Molecular Weight

21,893 Da

OMIM

607587

3D Structure

ModBase 3D Structure for Q8TAD2

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Immobilized rHuIL-17D binds to rHuIL-17BR with EC50 less than 2 ug/ml.

Solubility

It is recommended to reconstitute the lyophilized IL-17D in sterile 18M-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for IL17D active protein

Cytokines and Growth Factors

Other Notes

Small volumes of IL17D active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL17D purchase

MBS140979 is an active protein targeting IL17D. Also known as Recombinant Human Interleukin-17D. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for IL17D. It may not necessarily be applicable to this product.

NCBI GI #

19923715

NCBI GeneID

53342

NCBI Accession #

NP_612141.1

UniProt Primary Accession #

Q8TAD2

UniProt Secondary Accession #

B1AM69

UniProt Related Accession #

Q8TAD2

GenBank Nucleotide #

NM_138284.1

NCBI Official Full Name

interleukin-17D

NCBI Official Synonym Full Names

interleukin 17D

NCBI Official Symbol

IL17D

NCBI Official Synonym Symbols

IL27; IL-27; IL-17D

UniProt Protein Name

Interleukin-17D

UniProt Synonym Protein Names

Interleukin-27; IL-27

Protein Family

Interleukin

UniProt Gene Name

IL17D

UniProt Synonym Gene Names

IL27; IL-17D; IL-27

UniProt Entry Name

IL17D_HUMAN

NCBI Protein Information

interleukin-17D

UniProt Comments for IL17D

IL17D: Induces expression of IL-6, IL-8, and GM-CSF from endothelial cells. Belongs to the IL-17 family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 13q11

Cellular Component: extracellular space

Molecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding

Biological Process: cell surface receptor linked signal transduction; inflammatory response

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IL17D active protein

Products by Pathway	Pathway Diagram
IL17 Signaling Pathway antibodies	IL17 Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram

Diseases associated with IL17D active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>3 publications with IL17D and Inflammation
Necrosis Antibodies	>2 publications with IL17D and Necrosis
Kidney Diseases Antibodies	>1 publications with IL17D and Kidney Diseases
Renal Insufficiency Antibodies	>1 publications with IL17D and Renal Insufficiency
Weight Loss Antibodies	>1 publications with IL17D and Weight Loss

Organs/Tissues associated with IL17D active protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>3 publications with IL17D and Heart
Bone Antibodies	>2 publications with IL17D and Bone
Muscle Antibodies	>1 publications with IL17D and Muscle
Embryonic Tissue Antibodies	>1 publications with IL17D and Embryonic Tissue
Skin Antibodies	>1 publications with IL17D and Skin
Lung Antibodies	>1 publications with IL17D and Lung
Pancreas Antibodies	>1 publications with IL17D and Pancreas
Brain Antibodies	>1 publications with IL17D and Brain