Human INFA2 Active Protein – Cat# MBS9718715

Fig.SDS-PAGE analysis of Human IFN alpha 2 protein.

IFN Alpha 2 (INFA2) Human Active Protein

Name: INFA2 Active Protein; IFN Alpha 2; Human; MyBioSource
Brand: MyBioSource
SKU: MBS9718715
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9718715

Human interferon alpha-2 (IFNalpha2) is a cytokine belonging to the family of type I IFNs. IFNalpha2 is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. The first description of IFNs as a cellular agent… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

IFN alpha 2 (INFA2), Active Protein

Full Product Name

Human IFN alpha 2 Protein

Product Gene Name

INFA2 active protein

Product Synonym Names

Recombinant Human IFN alpha 2 Protein (Interferon alpha-2) expressed in Yeast; IFN-alphaA; IFNA; IFNA2B; IFNAB; Interferon alpha 2; Interferon alpha-2; IFNA2

Sequence

Amino acid sequence derived from human IFNA2 (NP_000596 .2) (Cys24-Glu 188) was expressed.

Host

Yeast

Form/Format

Lyophilized from sterile PBS, pH 7.4.

Purity/Purification

>95% as determined by SDS-PAGE.

Preparation and Storage

Item should be stored desiccated below -20 degree C. Upon reconstitution, the protein should be stored at 4 degree C between 2-7 days and for future use below -20 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Molecular Weight

19.3 kDa

3D Structure

ModBase 3D Structure for P01563

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Species

Human

Protein Length

The recombinant human IFNA2 consists 165 amino acids and predicts a molecular mass of 19.3 kDa.

Activity

Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus(VSV). The EC50 for this effect is typically 0.6-4.2pg/mL.

Usage Notes

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IFN alpha 2 protein in sterile ddH2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Other Notes

Small volumes of INFA2 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INFA2 purchase

MBS9718715 is an active protein targeting INFA2. Also known as Human IFN alpha 2 Protein. Host: Yeast.

Additional Details

NCBI/Uniprot data below describe general gene information for INFA2. It may not necessarily be applicable to this product.

NCBI GI #

11067751

NCBI GeneID

3440

NCBI Accession #

NP_000596.2

UniProt Primary Accession #

P01563

UniProt Related Accession #

P01563

GenBank Nucleotide #

NP_000596.2

NCBI Official Full Name

interferon alpha-2

NCBI Official Synonym Full Names

interferon alpha 2

NCBI Official Symbol

IFNA2

NCBI Official Synonym Symbols

IFNA; INFA2; IFNA2B; IFN-alphaA

Protein Family

Translation initiation factor

NCBI Protein Information

interferon alpha-2

NCBI Summary for INFA2

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]

Research Articles on INFA2

1. knockdown of STAT3 increased the phosphorylation of STAT1, and IFNalpha2b further enhanced the activation of STAT1 signaling in HepG2 cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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