4-Vinylphenol Inhibitor

98%

Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years

120.151

Oc1ccc(C=C)cc1

C8H8O

2628-17-3

Apoptosis|||Endogenous Metabolite

DMSO: 145mg/mL (1206.82 mM),
Need ultrasonic
(<1mg/mL refers to the product slightly soluble or insoluble)

4-Vinylphenol (100 ug/mL significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis. 4-Vinylphenol (50, 100 ug/mL significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol (12.5-200 ug/mL significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 ug/mL 4-Vinylphenol (0.15, 0.3 ug/mL reduces sphere?formation and vimentin expression on CSCs in breast cancer. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells[1].

Apoptosis; Metabolism