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5-hydroxy-7,8-dimethoxyflavone Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752123

5-hydroxy-7,8-dimethoxyflavone has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
5-hydroxy-7,8-dimethoxyflavone, Inhibitor
Full Product Name
5-hydroxy-7,8-dimethoxyflavone
Product Synonym Names
Moslosooflavone
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
298.29
Formula
C17H14O5
CAS
3570-62-5
Smiles
COc1cc(O)c2c(oc(cc2=O)-c2ccccc2)c1OC
Receptor (IC50)
NF-kappaB
Solubility
(<1mg/ml refers to the product slightly soluble or insoluble)

Product References and Citations for 5-hydroxy-7,8-dimethoxyflavone, inhibitor

1. Chao W W, Kuo Y H, Lin B F. Anti-inflammatory Activity of New Compounds from Andrographis paniculata by NF-B Transactivation Inhibition[J]. Journal of Agricultural and Food Chemistry, 2010, 58 (4):2505-2512.
2. Jing L L, He L, Fan P C, et al. [Chemical Constituents with Anti-hypoxia Activity from Saussurea involucrata][J]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, 38 (1):89-92.

Other Notes

Small volumes of 5-hydroxy-7,8-dimethoxyflavone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5752123 is an inhibitor targeting 5-hydroxy-7,8-dimethoxyflavone.
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