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Acumapimod Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752507

MBS5752507 is an inhibitor targeting Acumapimod. Acumapimod is an orally active inhibitor of p38alpha MAPK (IC50 More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Acumapimod, Inhibitor
Full Product Name
Acumapimod
Product Synonym Names
BCT-197
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
385.42
Formula
C22H19N5O2
CAS
836683-15-9
Smiles
Cc1ccc(cc1-n1ncc(C(=O)c2cccc(c2)C#N)c1N)C(=O)NC1CC1
Receptor (IC50)
p38alpha: <1uM
Solubility
DMSO: 50mg/mL (129.73mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Acumapimod, inhibitor

Home; MAPK; p38 MAPK

Structure of Acumapimod, inhibitor

Acumapimod Inhibitor – Cat# MBS5752507

Product References and Citations for Acumapimod, inhibitor

1. Growcott E J, Bamba D, Galarneau J. R, et al. The effect of P38 MAP kinase inhibition in a mouse model of influenza[J]. Journal of Medical Microbiology, 2018, 67 (3).
2. De Buck S, Hueber W, Vitaliti A, et al. Population PK-PD Model for Tolerance Evaluation to the p38 MAP Kinase Inhibitor BCT197[J]. CPT: Pharmacometrics & Systems Pharmacology, 2015, 4 (12):691-700.

Other Notes

Small volumes of Acumapimod, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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