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Allethrin Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5774787

Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Allethrin, Inhibitor
Full Product Name
Allethrin
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
302.414
SMILES
CC(C)=CC1C(C(=O)OC2CC(C)=C(CC=C)C2=O)C1(C)C
Formula
C19H26O3
CAS Number
584-79-2
Target
BCL|||Caspase
Solubility
DMSO: 60mg/mL (198.41 mM)
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
In male wistar rats aged 90 day,s Allethrin (25, 50, 100, and 150mg/kg; every day for 60 days) increased lipid peroxidation in the caput, cauda, and testes[3]. Significant increase in catalase activity was observed in the cauda obtained from 50, 100, and 150mg/kg. GPx activity was significantly increased in the caput obtained from 150mg/kg treated rats. In the cauda, it was found to be increased significantly in the 50 and 100mg/kg treated groups. In contrast, the activity of GPx activity was significantly decreased in the testes of rats treated with 150mg/kg. GST activity was found to be increased significantly in a dose dependent manner in the caput and cauda of allethrin treated rats[2].

Structure of Allethrin, inhibitor

Allethrin, CAS 584-79-2
Allethrin Inhibitor – Cat# MBS5774787

Structure of Allethrin, inhibitor

Allethrin, CAS 584-79-2
Allethrin Inhibitor, Structure – Cat# MBS5774787

Product References and Citations for Allethrin, inhibitor

1 Goll Madhubabu e al Allethri induce oxidativ stress apoptosi an calcu releas i ra testicula carcinom cell (LC540) Toxico I Vitro 201 Dec 8(8):1386-95.
2 Goll Madhubabu e al Allethri induce toxicit i th mal reproductiv trac o rat contribute t disruptio i th transcriptio o gene involve i ger cel production Enviro Toxicol 201 Nov 9(11):1330-45.
3 Geetik Gupta e al Allethri toxicit o PUMA cornea epithelia cell involve mitochondria pathwa mediate apoptosis Toxico I Vitro 201 Dec 7(8):2242-8.

Other Notes

Small volumes of Allethrin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Allethrin purchase

MBS5774787 is an inhibitor targeting Allethrin.
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