ARS-1630 Inhibitor

Name: ARS-1630 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752720
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752720

ARS-1630 is a mutant K-ras G12C inhibitor extracted from patent WO 2015054572 A1. It is a less active enantiomer of ARS-1620. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ARS-1630, Inhibitor

Full Product Name

ARS-1630

Product Gene Name

ARS-1630, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

430.84

Solubility

DMSO: 69mg/mL (160.15mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C21H17ClF2N4O2

SMILES

C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1)=O.[R]

CAS Number

1698055-86-5

Target & IC50

KRAS G12C

Product Categories/Family for ARS-1630, inhibitor

MAPK; Ras

Product References and Citations for ARS-1630, inhibitor

Liansheng Li, et al. Inhibitors of kras g12c. WO 2015054572 A1.
Liansheng Li, et al. Inhibitors of kras g12c. WO 2015054572 A1.
Janes MR, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 2018 Jan 25;172(3):578-589.e17.
Janes MR, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 2018 Jan 25;172(3):578-589.e17.

Other Notes

Small volumes of ARS-1630, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARS-1630 purchase

MBS5752720 is an inhibitor targeting ARS-1630.