• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ASTX660 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764287

MBS5764287 is an inhibitor targeting ASTX660. ASTX660 is an orally bioavailable dual antagonist of cIAP and XIAP. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ASTX660, Inhibitor
Full Product Name
ASTX660
Product Gene Name
ASTX660, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
539.68
Solubility
DMSO: 47mg/mL (87.09mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C30H42FN5O3
SMILES
C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nc(CO)c(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1
CAS Number
1799328-86-1
In Vitro
In HCC1806 xenografts in mice, ASTX660 (daily oral treatment, causes moderate tumor growth inhibition but not regression.

Product Categories/Family for ASTX660, inhibitor

Apoptosis; IAP

Product References and Citations for ASTX660, inhibitor

Tomoko Smyth, et al. Abstract 1287: The dual IAP antagonist, ASTX660, increases the anti-tumor activity of paclitaxel in preclinical models of triple-negative breast cancer in vivo. Cancer Res 2016;76(14 Suppl).

Other Notes

Small volumes of ASTX660, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000