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BAY 61-3606 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750413

BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BAY 61-3606, Inhibitor
Full Product Name
BAY 61-3606
Product Synonym Names
Syk
Form/Format
POWDER
Purity/Purification
98.9%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
390.4
CAS Number
732983-37-8
Formula
C20H18N6O3
Smiles
COc1ccc(cc1OC)-c1cc2nccn2c(Nc2ncccc2C(N)=O)n1
Solubility
DMSO: 10 mM
Pathways
Angiogenesis
Receptor
Syk
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of BAY 61-3606, inhibitor

BAY 61-3606 Inhibitor – Cat# MBS5750413

Product References and Citations for BAY 61-3606, inhibitor

1. Yamamoto N, et al. The orally available spleen tyrosine kinase inhibitor 2-[7-(3,4-dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents. J Pharmacol Exp Ther. 2003 Sep; 306(3):1174-81

Other Notes

Small volumes of BAY 61-3606, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAY 61-3606 purchase

MBS5750413 is an inhibitor targeting BAY 61-3606.
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