BCTC Inhibitor

Name: BCTC Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752320
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752320

BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6nM, respectively) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BCTC, Inhibitor

Full Product Name

BCTC

Product Gene Name

BCTC, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

372.89

Formula

C20H25ClN4O

CAS

393514-24-4

Smiles

CC(C)(C)c1ccc(NC(=O)N2CCN(CC2)c2ncccc2Cl)cc1

Receptor (IC50)

TRPV1/8

Solubility

DMSO: 50mg/mL (134.09mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for BCTC, inhibitor

Home; Membrane transporter/Ion Channel

Product References and Citations for BCTC, inhibitor

1. Gavva, N. R. Proton activation does not alter antagonist interaction with the capsaicin-binding pocket of TRPV1[J]. Molecular Pharmacology, 2005, 68 (6):1524---1533.
2. Liu T, Fang Z, Wang G, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells[J]. Oncology Letters, 2015.

Other Notes

Small volumes of BCTC, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BCTC purchase

MBS5752320 is an inhibitor targeting BCTC.