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BI-69A11 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5774884

BI-69A11 is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BI-69A11, Inhibitor
Full Product Name
BI-69A11
Product Gene Name
Product Synonym Names
BI 69A11; BI69A11; (E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one
Purity/Purification
90%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
425.87
SMILES
Oc1nc2ccc(Cl)cc2c(-c2ccccc2)c1C(=O)\C=C\c1nc2ccccc2[nH]1
Formula
C25H16ClN3O2
CAS Number
1233322-09-2
Target
NF-kappaB|||Akt
Solubility
DMSO: 55mg/mL (129.15 mM)
(<1mg/mL refers to the product slightly soluble or insoluble)

Structure of BI-69A11, inhibitor

BI-69A11, CAS 1233322-09-2
BI-69A11 Inhibitor – Cat# MBS5774884

Structure of BI-69A11, inhibitor

BI-69A11, CAS 1233322-09-2
BI-69A11 Inhibitor, Structure – Cat# MBS5774884

Product References and Citations for BI-69A11, inhibitor

1 Pa I Sarka S e al BI-69A1 enhance susceptibilit o colo cance cell t mda-7/IL-24-induce growt inhibitio b targetin Akt B Cancer 201 Ju 8 11(1):101-11.
2 Pa I Parid S e al Blockad o autophag enhance proapoptoti potentia o BI-69A11 nove Ak inhibitor i colo carcinoma Eu Pharmacol 201 Oc 15 65:217-27.
3 Fen Y La E e al Inhibitio o melanom developmen i th Nras((Q61K) :Ink4a(-/- mous mode b th smal molecul BI-69A11 Pigmen Cel Melanom Res 201 Jan 6(1):136-42 href="javascript:void(0) rel="nofollow >
4 Pa I De KK Chaurasi M Parid S Da S Rajes Y Sharm K Chowdhur T Manda M Cooperativ effec o BI-69A1 an celecoxi enhance radiosensitizatio b modulatin DN damag repai i colo carcinoma uMou Biol 201 May 7(5):6389-402 doi 10.1007/s13277-015-4399-6 Epu 201 De 2 PubMe PMID 26631035.

Other Notes

Small volumes of BI-69A11, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BI-69A11 purchase

MBS5774884 is an inhibitor targeting BI-69A11.
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