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CIQ Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754720

CIQ is a subunit-selective potentiator of nMDA receptors containing the NR2C or NR2D subunit (EC50s: 2.7 uM for NR2C and 2.8 uM for NR2D. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CIQ, Inhibitor
Full Product Name
CIQ
Product Gene Name
CIQ, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
467.94
Solubility
DMSO: 50mg/mL (106.85mM)
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C26H26ClNO5
SMILES
O=C(C1=CC=CC(Cl)=C1)N2C(COC3=CC=C(OC)C=C3)C4=C(C=C(OC)C(OC)=C4)CC2
CAS Number
486427-17-2
Target & IC50
Others
In Vitro
CIQ increases channel opening frequency of recombinant NR2C or NR2D containing receptors by two-fold, with no effect on NR2A or NR2B subtypes. CIQ does not alter the EC50 values for glutamate or glycine on channel opening. CIQ increases channel opening efficiency and enhances nMDA receptor responses. CIQ reduces associated behaviors in schizophrenia models and potentially enhances dopamine release in Parkinson's disease models.

Structure of CIQ, inhibitor

CIQ Inhibitor – Cat# MBS5754720

Other Notes

Small volumes of CIQ, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CIQ purchase

MBS5754720 is an inhibitor targeting CIQ.
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