Clovamide Inhibitor

Trans-Clovamide is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprotective effects (EC50s = 0.9-3.7uM) in several in vitro models of neuronal death. Trans-Clovamide is an excellent ROS and oxygen radical scavenger and also has anti-inflammatory and neuroprotective effects. Clovamide is an anti-microbial with activity against the Human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori.

1 Naik Ye e al Antioxidan studie b hydrodynami voltammetr an DFT quantitativ analyse b HPLC-DA o clovamide natura phenoli compoun foun i Theobrom Caca L beans Foo Chem 202 Ma 30 41(P 2):128260.
2 Fallarini e al Clovamid an rosmarini aci induc neuroprotectiv effect i i vitr model o neurona death B Pharmacol 200 Jul 57(6):1072-84.

Small volumes of Clovamide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5776015 is an inhibitor targeting Clovamide.