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Crisaborole Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750432

MBS5750432 is an inhibitor targeting Crisaborole. AN-2728 is a Phosphodiesterase 4 Inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Crisaborole, Inhibitor
Full Product Name
Crisaborole
Product Synonym Names
PDE
Form/Format
POWDER
Purity/Purification
99.9%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
251.05
CAS Number
906673-24-3
Formula
C14H10BNO3
Smiles
B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
Solubility
DMSO: >=32 mg/mL
Pathways
Metabolism
Receptor
PDE4
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Crisaborole, inhibitor

Inflammation

Chemical Structure of Crisaborole, inhibitor

Crisaborole Inhibitor – Cat# MBS5750432

Product References and Citations for Crisaborole, inhibitor

1. Akama T, et al. Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis. Bioorg Med Chem Lett. 2009 Apr 15; 19(8):2129-32.

Other Notes

Small volumes of Crisaborole, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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