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E7016 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5803897

E7016 (GPI 21016) is an orally available PARP Inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
E7016, Inhibitor
Full Product Name
E7016
Product Gene Name
E7016, inhibitor
Product Synonym Names
GPI 21016
Purity/Purification
98.16%
Preparation and Storage
Powder: -20 degree C for 3 years | In solvent: -80 degree C for 1 year
Molecular Weight
349.38
SMILES
O=C1C2=C3C(C=4C(OC3=CC=C2)=CC=C(CN5CCC(O)CC5)C4)=NN1
Formula
C20H19N3O3
Solubility
DMSO: 22.5 mg/mL (64.4 mM)
ultrasonic and warming and heat to 60 degree C
(< 1 mg/ml refers to the product slightly soluble or insoluble)
CAS Number
902128-92-1
In_vitro
Administration of E7016 (40 mg/kg; oral gavage) to mice bearing U251 xenografts enhances the effectiveness of the Temozolomide/radiation combination. Mice treated with E7016/irradiation/Temozolomide have an additional growth delay of six days compared with the combination of irradiation/Temozolomide in vivo[1].

Structure of E7016, inhibitor

E7016 Inhibitor – Cat# MBS5803897

Other Notes

Small volumes of E7016, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for E7016 purchase

MBS5803897 is an inhibitor targeting E7016.
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