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Erdafitinib Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS579723

MBS579723 is an inhibitor targeting Erdafitinib. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Erdafitinib, Inhibitor
Full Product Name
Erdafitinib
Form/Format
POWDER
Purity/Purification
99.04%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
446.55
CAS
1346242-81-6
Formula
C25H30N6O2
Pathways
Angiogenesis; Tyrosine Kinase/Adaptors
Target
FGFR1/2/3/4
Smiles
COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(nc2c1)-c1cnn(C)c1
Receptor
FGFR1; FGFR2; FGFR3; FGFR4
Bioactivity
Erdafitinib is a quinoxaline derivative compound, acts on FGFR1/2/3/4 with mean pIC50 of ~ 9/8.5/8.5/8.25, respectively.
Solubility
DMSO: 89mg/ml (199.31 mM); Water: <1mg/ml; Ethanol: 89mg/ml (199.31 mM)
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Erdafitinib, inhibitor

Cancer

Structure of Erdafitinib, inhibitor

Erdafitinib Inhibitor – Cat# MBS579723

Product References and Citations for Erdafitinib, inhibitor

1. Timothy Perera, et al. Cancer Res. 2014, 74 (19 Suppl):Abstract nr 1738. [2] Verstraete M, et al. BMC Cancer. 2015, 15:946.

Other Notes

Small volumes of Erdafitinib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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