Fenebrutinib Inhibitor

Name: Fenebrutinib Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5764494
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764494

Fenebrutinib (GDC-0853) is a selective and noncovalent Btk inhibitor (Ki: 0.91nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fenebrutinib, Inhibitor

Full Product Name

Fenebrutinib

Product Synonym Names

GDC-0853

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

664.8

Solubility

DMSO: 20mg/mL (30.09mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C37H44N8O4

SMILES

C[C@@H](CN(CC1)C2COC2)N1c(cc1)cnc1NC1=CC(c2c(CO)c(N(CCn3c4cc5c3CC(C)(C)C5)C4=O)ncc2)=CN(C)C1=O

CAS Number

1434048-34-6

Product Categories/Family for Fenebrutinib, inhibitor

Angiogenesis; BTK; Tyrosine Kinase/Adaptors

Product References and Citations for Fenebrutinib, inhibitor

Erickson RI, et al. Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats. J Pharmacol Exp Ther. 2017 Jan;360(1):226-238.

Other Notes

Small volumes of Fenebrutinib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fenebrutinib purchase

MBS5764494 is an inhibitor targeting Fenebrutinib.