• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GSK461364 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750128

MBS5750128 is an inhibitor targeting GSK461364. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK461364, Inhibitor
Full Product Name
GSK461364
Product Gene Name
GSK461364, inhibitor
Form/Format
POWDER
Purity/Purification
99.00%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
543.6
CAS
929095-18-1
Formula
C27H28F3N5O2S
Pathways
Cell Cycle/Checkpoint
Target
PLK1
Smiles
c1(c(cc(s1)n1cnc2c1cc(cc2)CN1CCN(CC1)C)O[C@H](C)c1c(cccc1)C(F)(F)F)C(=O)N
Receptor
PLK1
Bioactivity
GSK461364 inhibits purified Plk1 with Ki of 2.2 nM. It is more than 1000-fold selective against Plk2/3. Phase 1.
Solubility
DMSO: 10mg/ml (18.4 mM); Water: <1mg/ml; Ethanol: 30mg/ml (55.19 mM)
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for GSK461364, inhibitor

Cancer

Structure of GSK461364, inhibitor

GSK461364 Inhibitor – Cat# MBS5750128

Product References and Citations for GSK461364, inhibitor

1. Gilmartin AG, et al. Cancer Res, 2009, 69 (17), 6969-6977.

Other Notes

Small volumes of GSK461364, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000