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ML 18 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750120

MBS5750120 is an inhibitor targeting ML 18. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ML 18, Inhibitor
Full Product Name
ML 18
Product Gene Name
ML 18, inhibitor
Form/Format
POWDER
Purity/Purification
99.5%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
569.65
CAS
1422269-30-4
Formula
C32H35N5O5
Pathways
GPCR/G Protein
Target
BRS-3
Smiles
COc1ccc(cc1)C1(CCCCC1)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(cc1)[N+](=O)[O-]
Receptor
BRS-3
Bioactivity
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 muM.
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Structure of ML 18, inhibitor

ML 18 Inhibitor – Cat# MBS5750120

Product References and Citations for ML 18, inhibitor

1. Moody TW, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb; 64:55-61.

Other Notes

Small volumes of ML 18, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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