ML162 Inhibitor

Name: ML162 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5765103
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5765103

ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 for HRASG12V-expressing and wild-type BJ fibroblasts, respectively) More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ML162, Inhibitor

Full Product Name

ML162

Product Gene Name

ML162, inhibitor

Form/Format

Solid

Purity/Purification

0.9842

Preparation and Storage

Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).

Molecular Weight

477.4

Solubility

DMSO: 10mM
(<1mg/ml refers to the product slightly soluble or insoluble)

SMILES

COC1=C(C=C(C=C1)N(C(C2=CC=CS2)C(=O)NCCC3=CC=CC=C3)C(=O)CCl)Cl

Formula

C23H22Cl2N2O3S

CAS Number

1035072-16-2

Product Categories/Family for ML162, inhibitor

Oxidation-reduction; GPX

Product References and Citations for ML162, inhibitor

WeiWer M, Bittker J A, Lewis T A, et al. Development of small-molecule probes that selectively kill cells induced to express mutant RAS[J]. Bioorganic & Medicinal Chemistry Letters, 2012, 22(4):1822-1826.

Other Notes

Small volumes of ML162, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ML162 purchase

MBS5765103 is an inhibitor targeting ML162.