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NMS-P515 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5769695

NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16nM and an IC50: 27nM (in Hela cells)). It has anti-tumor activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NMS-P515, Inhibitor
Full Product Name
NMS-P515
Product Gene Name
NMS-P515, inhibitor
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
Molecular Weight
355.482
SMILES
C[C@@H]1N(C2CCN(CC2)C2CCCCC2)C(=O)c2c1cccc2C(N)=O
Formula
C21H29N3O2
CAS Number
1262395-13-0
Target
Others
PARP-1: 16nM (kd), PARP-1: 27nM (in Hela cells)
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
NMS-P515 (80mg/kg; p.o.; 12 days) shows effective Antitumor activity in mouse models based on pancreatic cancer.

Product Categories/Family for NMS-P515, inhibitor

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Structure of NMS-P515, inhibitor

NMS-P515, CAS 1262395-13-0
NMS-P515 Inhibitor – Cat# MBS5769695

Structure of NMS-P515, inhibitor

NMS-P515, CAS 1262395-13-0
NMS-P515 Inhibitor, Structure – Cat# MBS5769695

Product References and Citations for NMS-P515, inhibitor

1 Pape G e al Discover o Stereospecifi PARP- Inhibito IsoindolinonenMS-P515 AC Me Che Lett 201 Ma 13 0(4):534-538.

Other Notes

Small volumes of NMS-P515, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NMS-P515 purchase

MBS5769695 is an inhibitor targeting NMS-P515.
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