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NSC 405020 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS385831

NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L). More details

$160 / 10 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NSC 405020, Inhibitor
Full Product Name
NSC 405020
Product Synonym Names
NSC405020; NSC-405020
Form/Format
Powder
Purity/Purification
>98%
Concentration
0.1 mM: 38.44 mL (1 mg); 192.19 mL (5 mg); 384.38mL (10 mg)
0.5 mM: 7.69 mL (1 mg); 38.44 mL (5 mg); 76.88 mL (10 mg)
1 mM: 3.84 mL (1 mg); 19.22 mL (5 mg); 38.44 mL (10 mg)
5 mM: 0.77 mL (1 mg); 3.84 mL (5 mg); 7.69 mL (10 mg) (lot specific)
Preparation and Storage
at -20 degree C 3 years Powder
Molecular Weight
260.16
CAS Number
CAS: 7497-07-6
Formula
C12H15Cl2NO
SMILES
CCCC(C)NC(=O)C1=CC(=C(C=C1)Cl)Cl
Actions
Inhibitor
In Vivo Solvent
1% DMSO/30% polyethylene glycol/1% Tween 80
Solubility (DMSO)
52 mg/mL (199.87 mM)
Solubility (Ethanol)
52 mg/mL (199.87 mM)
Solubility (in vivo)
5 mg/mL
Solubility (Water)
<1 mg/mL (<1 mM)
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.

Chemical Structure of NSC 405020, inhibitor

NSC 405020 Inhibitor – Cat# MBS385831

Product References and Citations for NSC 405020, inhibitor

Kittaka M, .et al. Cherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts, J Bone Miner Res, 2018, Jan;33(1):167-181 PMID: 28914985

Other Notes

Small volumes of NSC 405020, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NSC 405020 purchase

MBS385831 is an inhibitor targeting NSC 405020.
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