Pactimibe Inhibitor

MBS5777981 is an inhibitor targeting Pactimibe. Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity.

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1 KotuM M Toku T Freudenthale S Nishimur K Effec o CYP2D polymorphis o pharmacokinetic o nove ACA inhibitor pactimib an it uniqu metabolite R-125528 In Cli Pharmaco Ther 200 Nov 6(11):545-55 PubMe PMID 19000552 href="javascript:void(0) rel="nofollow >
2 KotuM M Toku T Freudenthale S Nishimur K Effect o ketoconazol an quinidin o pharmacokinetic o pactimib an it plasm metabolite R-125528 i Humans Dru Meta Dispos 200 Aug 6(8):1505-11 doi 10.1124/dmd.108.021394 PubMe PMID 18448569 href="javascript:void(0) rel="nofollow >
3 KotuM M Hanzaw H Iwat Y Takahash K Toku T Nove bindin mod o th acidi CYP2D substrate pactimib an it metabolit R-125528 Dru Meta Dispos 200 Sep 6(9):1938-43 doi 10.1124/dmd.108.020776 PubMe PMID 18524873 href="javascript:void(0) rel="nofollow >
4 Kitayam K Tanimot T Kog T Terasak N Fujiok T Inab T Importanc o acyl-coenzym A:cholestero acyltransferas 1/ dua inhibitio fo anti-atheroscleroti potenc o pactimibe Eu Pharmacol 200 Ju 1 40(1-3):121-30 PubMe PMID 16730694.

Small volumes of Pactimibe, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.