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PP242 (Torkinib) Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS385978

MBS385978 is an inhibitor targeting PP242 (Torkinib). PP242 is a potent and selective mTOR inhibitor in both mTORC1 and mTORC2. More details

$155 / 1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PP242 (Torkinib), Inhibitor
Full Product Name
PP242 (Torkinib)
Product Synonym Names
PP-242
Form/Format
Powder
Purity/Purification
>98%
Concentration
0.1 mM: 32.44 mL (1 mg); 162.18 mL (5 mg); 324.36mL (10 mg)
0.5 mM: 6.49 mL (1 mg); 32.44 mL (5 mg); 64.87 mL (10 mg)
1 mM: 3.24 mL (1 mg); 16.22 mL (5 mg); 32.44 mL (10 mg)
5 mM: 0.65 mL (1 mg); 3.24 mL (5 mg); 6.49 mL (10 mg) (lot specific)
Preparation and Storage
at -20 degree C 3 years Powder
Molecular Weight
308.3
CAS Number
1092351-67-1
Formula
C16H16N6O
SMILES
CC(C)N1C2=C(/C(=C\3/C=C4C=C(C=CC4=N3)O)/N1)C(=NC=N2)N
Actions
Inhibitor
In Vivo Solvent
30% PEG400/0.5% Tween80/5% propylene glycol
Solubility (DMSO)
62 mg/mL (201.07 mM)
Solubility (Ethanol)
18 mg/mL (58.37 mM)
Solubility (in vivo)
30 mg/mL
Solubility (Water)
<1 mg/mL (<1 mM)
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.

Chemical Structure of PP242 (Torkinib), inhibitor

PP242 (Torkinib) Inhibitor – Cat# MBS385978

Product References and Citations for PP242 (Torkinib), inhibitor

Hiroshi Fukamachi, .et al. A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors, J Exp Clin Cancer Res, 2019, 38:127
Fuse MJ, .et al. Mechanisms of Resistance to NTRK Inhibitors and Therapeutic Strategies in NTRK1-Rearranged Cancers, Mol Cancer Ther, 2017, Oct;16(10):2130-2143 PMID: 28751539

Other Notes

Small volumes of PP242 (Torkinib), inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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