• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

QS-21 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5785450

QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 uMoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with… More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
QS-21, Inhibitor
Full Product Name
QS-21
Product Gene Name
QS-21, inhibitor
Product Synonym Names
Stimulon
Purity/Purification
98%
Preparation and Storage
Powder: -2 degree C for 3 years
In solvent: -80 degree C for 2 years
CAS Number
141256-04-4
Solubility
(<1mg/mL refers to the product slightly soluble or insoluble)
In_vitro
Studies in mouse APCs (DCs and macrophages) identifie QS-21 as an activator of the NLRP3 inflammasome, and cause subsequent release of caspase-1 dependent proinflammatory cytokines I1-1beta/I1-18 that can promote Th 17 cell maturation or drive INF-gamma-mediated Th1 responses, respectively[3].

Structure of QS-21, inhibitor

QS-21, CAS 141256-04-4
QS-21 Inhibitor – Cat# MBS5785450

Structure of QS-21, inhibitor

QS-21, CAS 141256-04-4
QS-21 Inhibitor, Structure – Cat# MBS5785450

Product References and Citations for QS-21, inhibitor

1 Fernández-Tejad A e al Developmen o Improve Vaccin Adjuvant Base o th Saponi Natura Produc QS-2 throug Chemica Synthesis Ac Che Res 2016 9(9):1741-1756.
2 Marty-Roi R e al Identificatio o QS-2 a a Inflammasome-activatin Molecula Componen o Saponi Adjuvants Bio Chem 2016 91(3):1123-1136
3 Lacaille-Duboi MA Update insight int th mechanis o actio an clinica profil o th immunoadjuvan QS-21 review Phytomedicine 2019 0:152905.

Other Notes

Small volumes of QS-21, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for QS-21 purchase

MBS5785450 is an inhibitor targeting QS-21.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000